Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GALK1 | P51570 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | PLEC | Q15149 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570368 | 1.00 | MITF (0.50) | MITFALDH1A1POLBMAPK1HTT | |
| Trifluoroacetic Acid SCHEMBL20568992 | 0.85 | HDAC3 (0.54) | MITFALDH1A1POLBMAPK1HTT | |
| Trifluoroacetic Acid SCHEMBL20568990 | 0.85 | HDAC3 (0.54) | MITFALDH1A1POLBMAPK1HTT | |
| SCHEMBL20570047 | 0.83 | F10 (0.58) | — | |
| SCHEMBL20570050 | 0.83 | F10 (0.58) | — | |
| SCHEMBL14456468 | 0.82 | TAAR1 (0.56) | SCN9AFNTAFNTBPGGT1B | |
| SCHEMBL11642407 | 0.81 | MITF (0.57) | MITFALDH1A1POLBMAPK1HTT | |
| SCHEMBL2308107 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TSHR | |
| SCHEMBL14456427 | 0.80 | LTA4H (0.60) | FNTAFNTBPGGT1BHDAC4 | |
| SCHEMBL14467491 | 0.80 | PLAU (0.55) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |