Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30218709 | 0.88 | MGLL (0.49) | MGLL | |
| SCHEMBL20566495 | 0.88 | MGLL (0.49) | MGLL | |
| SCHEMBL20567101 | 0.86 | MGLL (0.74) | MGLLFAAH | |
| SCHEMBL30302064 | 0.86 | MGLL (0.74) | MGLLFAAH | |
| SCHEMBL24970488 | 0.85 | MGLL (0.62) | MGLLFAAH | |
| SCHEMBL20567736 | 0.85 | CYP3A4 (0.44) | MGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL30218711 | 0.85 | CYP3A4 (0.44) | MGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL20567352 | 0.81 | MGLL (0.65) | MGLLFAAH | |
| SCHEMBL30302098 | 0.81 | MGLL (0.65) | MGLLFAAH | |
| SCHEMBL25487662 | 0.76 | MGLL (0.49) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-A1 | PYRAZOLE MAGL INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018217805-A1 | PYRAZOLE MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-11-29 | — | — | WO | disclosed |