SCHEMBL24970488

SCHEMBL24970488

Cc1ccn(C(=O)N2CCC3(CCCN3Cc3cc(-n4cccn4)cc(C(F)(F)F)c3)CC2)n1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.62
FAAH O00519 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567101 0.90 MGLL (0.74) MGLLFAAH
SCHEMBL30302064 0.90 MGLL (0.74) MGLLFAAH
SCHEMBL30302098 0.88 MGLL (0.65) MGLLFAAH
SCHEMBL20567352 0.88 MGLL (0.65) MGLLFAAH
SCHEMBL20570797 0.85 MGLL (0.53) MGLLFAAH
SCHEMBL20566495 0.82 MGLL (0.49) MGLL
SCHEMBL30218709 0.82 MGLL (0.49) MGLL
SCHEMBL25488268 0.81 MGLL (0.52) MGLLFAAH
SCHEMBL25487659 0.81 MGLL (0.59) MGLLFAAH
SCHEMBL25487671 0.79 MGLL (0.52) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630744-B1 PYRAZOLE MAGL INHIBITORS H LUNDBECK AS (DK) 2023-01-25 EP disclosed