Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573268 | 0.86 | BCL9 (0.40) | ERN1MAPK1SLC9A1LRRK2FFAR4 | |
| SCHEMBL20573157 | 0.84 | ERN1 (0.45) | ERN1MAPTSLC9A1PTGS2LRRK2 | |
| SCHEMBL20573261 | 0.84 | BCL9 (0.44) | SLC9A1LRRK2 | |
| SCHEMBL17797025 | 0.82 | PARP1 (0.42) | RELAMAPK1SLC9A1MEN1KMT2A | |
| SCHEMBL17797023 | 0.81 | ERN1 (0.40) | ERN1SLC9A1MEN1KMT2ALRRK2 | |
| SCHEMBL20573251 | 0.81 | CHRM3 (0.42) | CYP3A4CYP2C19CYP2C9AHR | |
| SCHEMBL20573273 | 0.81 | ERN1 (0.41) | ERN1MAPTSLC9A1CYP1A2CYP3A4 | |
| SCHEMBL20573247 | 0.81 | SCN9A (0.47) | FFAR4 | |
| SCHEMBL17796980 | 0.80 | PTGDR2 (0.43) | MAPTFFAR4 | |
| SCHEMBL20573249 | 0.80 | CHRM3 (0.42) | MAPTSLC9A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |