Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083644 | 0.78 | KDM4E (0.49) | KDM4EHPGDLMNABLMALDH1A1 | |
| SCHEMBL3074222 | 0.77 | KDM4E (0.47) | KDM4EHPGDLMNABLMALDH1A1 | |
| SCHEMBL20364746 | 0.70 | MTNR1A (0.56) | KDM4EHPGDLMNABLMALDH1A1 | |
| SCHEMBL17689390 | 0.69 | CYP1A2 (0.53) | KDM4EHPGDLMNABLMALDH1A1 | |
| SCHEMBL1039416 | 0.69 | MTNR1A (0.63) | KDM4EHPGDLMNABLMALDH1A1 | |
| SCHEMBL4897761 | 0.68 | HPGD (0.45) | KDM4EHPGDLMNAALDH1A1MAPT | |
| Salicylic Acid SCHEMBL29208027 | 0.67 | ALDH1A1 (0.56) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL10888536 | 0.67 | NAAA (0.54) | KDM4EHPGDLMNABLMALDH1A1 | |
| SCHEMBL7858 | 0.67 | KDM4E (0.69) | KDM4EHPGDLMNABLMALDH1A1 | |
| SCHEMBL29575320 | 0.66 | TSHR (0.48) | KDM4EHPGDLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994535-B1 | PRODUCTION OF MYXOPYRONIN AND OF ITS DERIVATIVES | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2018-12-05 | — | — | EP | disclosed |