Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21867 | 0.82 | MEN1 (0.38) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL10253354 | 0.81 | KMT2A (0.38) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL14035693 | 0.79 | — | — | |
| SCHEMBL29362499 | 0.79 | MEN1 (0.38) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22286973 | 0.79 | MEN1 (0.38) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4440517 | 0.77 | G6PD (0.31) | — | |
| SCHEMBL752095 | 0.75 | — | — | |
| SCHEMBL20502028 | 0.75 | KMT2A (0.36) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10252604 | 0.74 | ALDH1A1 (0.39) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4765661 | 0.74 | MEN1 (0.38) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027236-A1 | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS | SCHERING CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |