⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466115 | 0.97 | — | — | |
| SCHEMBL2705709 | 0.91 | PLG (0.43) | — | |
| SCHEMBL239077 | 0.90 | — | — | |
| SCHEMBL573499 | 0.90 | ALDH1A1 (0.47) | — | |
| SCHEMBL25278102 | 0.89 | ALDH1A1 (0.41) | — | |
| SCHEMBL1543551 | 0.89 | MCL1 (0.39) | — | |
| SCHEMBL25278103 | 0.89 | ALDH1A1 (0.41) | — | |
| SCHEMBL20852085 | 0.88 | ALDH1A1 (0.50) | — | |
| SCHEMBL4842055 | 0.88 | ALDH1A1 (0.50) | — | |
| SCHEMBL26722615 | 0.88 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088513-A1 | 2-CYANO-3-CYCLOPROPYL-3-HYDROXY-N-ARYL-THIOACRYLAMIDE DERIVATIVES | ALGIAX PHARMACEUTICALS GMBH (DE) | 2017-03-30 | — | — | US | claimed |
| EP-3119744-A1 | 2-CYANO-3-CYCLOPROPYL-3-HYDROXY-N-ARYL-THIOACRYLAMIDE DERIVATIVES | Algiax Pharmaceuticals GmbH (DE) | 2017-01-25 | — | — | EP | claimed |
| WO-2015140081-A1 | 2-CYANO-3-CYCLOPROPYL-3-HYDROXY-N-ARYL-THIOACRYLAMIDE DERIVATIVES | ALGIAX PHARMACEUTICALS GMBH (DE) | 2015-09-24 | — | — | WO | claimed |
| EP-1361215-B1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-03-21 | — | — | EP | claimed |
| US-6841681-B2 | Process for producing quinoline carboxyaldehyde derivative and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-01-11 | — | — | US | claimed |
| US-20040077866-A1 | Process for producing quinoline carboxyaldehyde derivative and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-22 | — | — | US | claimed |
| EP-1361215-A1 | PROCESS FOR PRODUCING QUINOLINE CARBOXYALDEHYDE DERIVATIVE AND INTERMEDIATE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2003-11-12 | — | — | EP | claimed |
| EP-4741018-A2 | SULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2026-05-13 | — | — | EP | disclosed |
| CN-122029151-A | Statin derivatives and methods of use thereof | 通用医疗公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12611404-B2 | Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides | CHEMOCENTRYX, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| EP-4724426-A1 | STATIN DERIVATIVES AND METHODS OF USING THE SAME | The General Hospital Corporation (US) | 2026-04-15 | — | — | EP | disclosed |
| US-12583836-B2 | Sulphonamide compounds | Anaxis Pharma Pty Ltd (AU) | 2026-03-24 | — | — | US | disclosed |
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
| EP-0326107-B1 | ANTIARTHRITIC BETA-CYCLOALKYL-BETA-OXOPROPIONITRILES | Bristol-Myers Squibb Company (US) | 1992-09-02 | — | — | EP | disclosed |
| CN-1063682-A | Novel herbicide | RHONE POULENC AGRICULTURE (GB) | 1992-08-19 | — | — | CN | disclosed |
| EP-0496631-A1 | 2-Cyano-1,3-dione herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0496630-A1 | 2-Cyano-1,3-dione herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0490587-A1 | Substituted pyrazolopyrimidines and imidazopyridazines as angiotensin II antagonists | MERCK & CO. INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4888357-A | ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0326107-A1 | Antiarthritic beta-cycloalkyl-beta-oxopropionitriles | Bristol-Myers Squibb Company (US) | 1989-08-02 | — | — | EP | disclosed |