Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189760 | 0.94 | PTGS1 (0.41) | PTGS1PTGS2POLBMGLLFAAH | |
| SCHEMBL18081561 | 0.91 | PTGS1 (0.46) | PTGS1PTGS2POLBMGLLFAAH | |
| SCHEMBL28516664 | 0.89 | MGLL (0.46) | PTGS1PTGS2POLBMGLLFAAH | |
| SCHEMBL16096373 | 0.88 | PTGS1 (0.45) | PTGS1PTGS2POLBMGLLFAAH | |
| SCHEMBL10005217 | 0.88 | PTGS1 (0.43) | PTGS1PTGS2POLBMGLLFAAH | |
| SCHEMBL13531990 | 0.88 | PTGS1 (0.47) | PTGS1PTGS2POLBMGLLFAAH | |
| SCHEMBL10005219 | 0.88 | PTGS1 (0.43) | PTGS1PTGS2POLBMGLLFAAH | |
| SCHEMBL19668514 | 0.87 | MGLL (0.45) | PTGS1PTGS2POLBMGLLALDH1A1 | |
| SCHEMBL17841910 | 0.87 | PTGS1 (0.61) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL17462703 | 0.86 | PTGS1 (0.42) | PTGS1PTGS2POLBMGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383846-B1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | OTAGO INNOVATION LTD (NZ) | 2022-06-22 | — | — | EP | disclosed |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | OTAGO INNOVATION LIMITED (NZ) | 2021-07-27 | — | — | US | disclosed |
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-04-09 | — | — | US | disclosed |
| US-20180346420-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | UNIVERSITY OF OTAGO (NZ) | 2018-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | HMOX1, MB, NOS2 | PTGS1 23/4885PTGS2 32/4885POLB 4692/4885 |
| US-20180346420-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | HMOX1, MB, NOS2 | PTGS1 23/4885PTGS2 32/4885POLB 4692/4885 |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | HMOX1, MB, NOS2 | PTGS1 23/4885PTGS2 32/4885POLB 4692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.