SCHEMBL5493096

SCHEMBL5493096

O=C(OC(=O)c1cc(Cl)c(Cl)c(Cl)c1Cl)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 2/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
HPGD P15428 3/20 0.39
PKM P14618 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
GAA P10253 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
MAPT P10636 3/20 0.38
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20577112 0.86 CYP3A4 (0.43) TSHRHPGDSMN1; SMN2GAAMAPT
SCHEMBL20513003 0.85 F2 (0.44) F2LMNATSHRNPC1RAB9A
SCHEMBL11557836 0.82 LMNA (0.48) F2LMNATSHRNPC1RAB9A
Ethyl Benzoate SCHEMBL2241358 0.79 TSHR (0.50) LMNATSHRNPC1RAB9ASMN1; SMN2
SCHEMBL2153557 0.79 SMN1; SMN2 (0.58) F2LMNATSHRNPC1RAB9A
SCHEMBL5079583 0.79 AKR1C3 (0.48) LMNATSHRHPGDPKML3MBTL1
SCHEMBL5955453 0.78 TSHR (0.56) F2LMNATSHRNPC1RAB9A
SCHEMBL6355098 0.77 CES2 (0.52) RAB9AHPGDPKMMAPTALDH1A1
SCHEMBL9815890 0.77 LMNA (0.50) F2LMNATSHRSMN1; SMN2MAPT
SCHEMBL3077888 0.77 RAB9A (0.62) TSHRNPC1RAB9AHPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247740-B2 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2007-07-24 US claimed
CN-118005003-B Ultra-micro porous hard carbon material and preparation method and application thereof 成都锂能科技有限公司 2024-06-18 CN disclosed
CN-118005003-A Ultra-micro porous hard carbon material and preparation method and application thereof 成都锂能科技有限公司 2024-05-10 CN disclosed
CN-115627559-B Degradable filament and special material thereof 北京微构工场生物技术有限公司 2023-05-16 CN disclosed
EP-4098683-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2022-12-07 EP disclosed
CN-114196227-A Process for the preparation of isoindolinone pigments 百合花集团股份有限公司 2022-03-18 CN disclosed
US-11034822-B2 Method for producing recycled thermoplastic rubber masterbatch with improved green strength and tack Tyrec Ltd. (IL) 2021-06-15 US disclosed
US-20200181372-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2020-06-11 US disclosed
EP-3630876-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2020-04-08 EP disclosed
WO-2018220618-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2018-12-06 WO disclosed
CN-1222519-A Preparation of tetrachlorobenzene anhydride ZHANG WEN (CN) 1999-07-14 CN disclosed