Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756628 | 0.95 | CYP4A11 (0.45) | CYP4A11CYP4F2CASP3SENP8SENP7 | |
| SCHEMBL30380929 | 0.95 | CYP4A11 (0.45) | CYP4A11CYP4F2CASP3SENP8SENP7 | |
| Lithium Ion SCHEMBL29886630 | 0.92 | CYP4A11 (0.42) | CYP4A11CYP4F2CASP3SENP8SENP7 | |
| SCHEMBL3229511 | 0.87 | NNMT (0.44) | CYP4A11CYP4F2NNMTGRM2DAO | |
| SCHEMBL20759038 | 0.84 | CASP3 (0.59) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL22792257 | 0.83 | CASP3 (0.57) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL19236921 | 0.83 | CASP3 (0.57) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL6014373 | 0.83 | HRH1 (0.45) | CASP3SENP8SENP7SENP6NNMT | |
| SCHEMBL13791527 | 0.82 | CASP3 (0.53) | CASP3SENP8SENP7SENP6KDM1A | |
| SCHEMBL16797047 | 0.82 | KDM4E (0.44) | CASP3SENP8SENP7SENP6NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018219478-A1 | HETEROARYL-CARBOXAMIDES AS HISTONE DEMETHYLASE INHIBITORS | ORYZON GENOMICS, S.A. (ES) | 2018-12-06 | — | — | WO | disclosed |