Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10767839 | 0.88 | EPHX1 (0.39) | EPHX1ALDH1A1MEN1KMT2ATRPM8 | |
| Hydrogen Peroxide SCHEMBL65467 | 0.85 | TRPA1 (0.41) | EPHX1ALDH1A1MEN1KMT2ATRPM8 | |
| SCHEMBL452781 | 0.84 | TRPA1 (0.39) | EPHX1ALDH1A1MEN1KMT2ATRPM8 | |
| SCHEMBL7979 | 0.84 | TRPA1 (0.39) | EPHX1ALDH1A1MEN1KMT2ATRPM8 | |
| SCHEMBL1760669 | 0.84 | TRPA1 (0.39) | EPHX1ALDH1A1MEN1KMT2ATRPM8 | |
| Carbamic Acid SCHEMBL1512882 | 0.84 | EPHX1 (0.46) | EPHX1ALDH1A1MEN1KMT2ATRPM8 | |
| SCHEMBL17698405 | 0.84 | EPHX1 (0.37) | EPHX1ALDH1A1MEN1KMT2ATRPM8 | |
| Charcoal, Activated SCHEMBL4530459 | 0.82 | TRPA1 (0.37) | EPHX1TRPM8TRPA1 | |
| Water SCHEMBL2851760 | 0.82 | TRPA1 (0.37) | EPHX1TRPM8TRPA1 | |
| Ammonia Solution, Strong SCHEMBL5944185 | 0.82 | TRPA1 (0.37) | EPHX1TRPM8TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949555-B | Physiological cooling compound | 西姆莱斯有限公司 | 2024-09-24 | — | — | CN | disclosed |
| US-20110160303-A1 | N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE | EDWARD TAK WEI | 2011-06-30 | — | — | US | disclosed |
| EP-2161252-A1 | N-Alkylcarbonyl-amino acid ester and N-Alkylcarbonyl-amino lactone compounds and their use | Wei, Edward T. (US) | 2010-03-10 | — | — | EP | disclosed |
| EP-1871738-B1 | N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE | WEI EDWARD T (US) | 2009-07-15 | — | — | EP | disclosed |
| US-20080227857-A1 | N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use | WEI EDWARD TAK | 2008-09-18 | — | — | US | disclosed |
| US-20070053834-A1 | Radioligands for the TRP-M8 receptor and methods therewith | WEI EDWARD T | 2007-03-08 | — | — | US | disclosed |
| US-7169377-B2 | Radioligands for the TRP-M8 receptor and methods therewith | WEI EDWARD T | 2007-01-30 | — | — | US | disclosed |
| US-20050187211-A1 | N-arylsalkyl-carboxamide compositions and methods | WEI EDWARD T (US) | 2005-08-25 | — | — | US | disclosed |
| WO-2005039649-A1 | RADIOLIGANDS FOR THE TRP-M8 RECEPTOR AND METHODS THEREWITH | PAGET, HUGH, C., E. (GB) | 2005-05-06 | — | — | WO | disclosed |
| US-20050084447-A1 | Radioligands for the TRP-M8 receptor and methods therewith | WEI EDWARD T (US) | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050084447-A1 | Radioligands for the TRP-M8 receptor and methods therewith | TRPM8, GPR68, OPRL1 | EPHX1 4381/4885ALDH1A1 1911/4885MEN1 735/4885 |
| US-20050187211-A1 | N-arylsalkyl-carboxamide compositions and methods | OPRL1, TRPV1, TRPA1 | EPHX1 1355/4885ALDH1A1 1506/4885MEN1 4824/4885 |
| US-20070053834-A1 | Radioligands for the TRP-M8 receptor and methods therewith | GPR68, TRPM8, OPRL1 | EPHX1 4778/4885ALDH1A1 1220/4885MEN1 1056/4885 |
| US-20080227857-A1 | N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use | TRPA1, TRPV1, CYSLTR1 | EPHX1 1517/4885ALDH1A1 2618/4885MEN1 3885/4885 |
| US-20110160303-A1 | N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE | TRPA1, TRPV1, CYSLTR1 | EPHX1 1517/4885ALDH1A1 2618/4885MEN1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.