SCHEMBL20577916

SCHEMBL20577916

C=Cc1ccccc1C[Si](C)(C)N([Si](C)(C)C)[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18135552 0.86 ALDH1A1 (0.30) ALDH1A1
SCHEMBL21467278 0.84 ALDH1A1 (0.35) ALDH1A1
SCHEMBL5995461 0.80 ALDH1A1 (0.40) ALDH1A1
SCHEMBL3747867 0.77 ALDH1A1 (0.42) ALDH1A1
SCHEMBL6291751 0.77 ALDH1A1 (0.38) ALDH1A1
SCHEMBL9715820 0.77 ALDH1A1 (0.42) ALDH1A1
SCHEMBL19931232 0.75
SCHEMBL6296635 0.74 ALDH1A1 (0.35) ALDH1A1
SCHEMBL3629863 0.72 ALDH1A1 (0.34) ALDH1A1
SCHEMBL6292788 0.72 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752721-B2 Elastomeric copolymers based on [bis(trihydrocarbylsilyl)aminosilyl]-functionalized styrene and their use in the preparation of rubbers SYNTHOS DWORY 7 SPOLKA Z ORGANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA (PL) 2020-08-25 US disclosed
US-10723822-B2 [Bis(trihydrocarbylsilyl)aminosilyl]-functionalized styrene and a method for its preparation SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA (PL) 2020-07-28 US disclosed
US-20190256624-A1 [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND A METHOD FOR ITS PREPARATION SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2019-08-22 US disclosed
EP-3341424-B1 ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA (PL) 2019-03-13 EP disclosed
EP-3341423-B1 [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND A METHOD FOR ITS PREPARATION Synthos Sa (PL) 2018-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190256624-A1 [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND A METHOD FOR ITS PREPARATION ADSL, PARN, STS ALDH1A1 1581/4885
US-10723822-B2 [Bis(trihydrocarbylsilyl)aminosilyl]-functionalized styrene and a method for its preparation ADSL, PARN, STS ALDH1A1 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.