SCHEMBL5995461

SCHEMBL5995461

C=Cc1ccccc1C[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3747867 0.84 ALDH1A1 (0.42) ALDH1A1
SCHEMBL9715820 0.84 ALDH1A1 (0.42) ALDH1A1
SCHEMBL21467278 0.81 ALDH1A1 (0.35) ALDH1A1
SCHEMBL3629863 0.80 ALDH1A1 (0.34) ALDH1A1
SCHEMBL20577916 0.80 ALDH1A1 (0.34) ALDH1A1
SCHEMBL9030704 0.79 LMNA (0.48) ALDH1A1TSHR
SCHEMBL7037729 0.79 ALDH1A1 (0.45) ALDH1A1TSHR
SCHEMBL2811181 0.79 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5913008 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3949037 0.77 ESR1 (0.40) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62209117-A None JP disclosed
US-7041761-B2 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-05-09 US disclosed
US-6901982-B2 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-06-07 US disclosed
US-20050049377-A1 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2005-03-03 US disclosed
US-20050006014-A1 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2005-01-13 US disclosed
US-6825306-B2 ADDITION COPOLYMERIZATION OF CONJUGATED DIENE AND STYRENE MONOMER FUNCTIONALIZED WITH SILYL(OXY)ALKYL GROUP; TIRES, HOSES; ANIONIC POLYMERIZATION THE GOODYEAR TIRE & RUBBER COMPANY 2004-11-30 US disclosed
EP-0742255-B1 Colouration of high molecular weight organic materials in the mass with soluble phthalocyanine precursors CIBA SC HOLDING AG (CH) 2004-04-14 EP disclosed
US-20040063884-A1 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2004-04-01 US disclosed
US-6180315-B1 FORMING POLYMER LAYER CONTAINING PATTERN OR IMAGE OF DISSOLVED PIGMENT PRECURSOR COMPONENT, POLYMER OR NATURAL OR SYNTHETIC RESIN, CATALYST FOR PIGMENT FORMATION; LOCALLY REGENERATING PIGMENT BY CHEMICAL, PHOTOLYTICAL, THERMAL OR LASER MEANS CIBA SPECIALTY CHEMCIALS CORPORATION 2001-01-30 US disclosed
US-6040108-A FORMING RESIN LAYER CONTAINING DISSOLVED ORGANIC PIGMENT PRECURSOR, IMAGEWISE PRECIPITATING COLORED NANO-SIZED PIGMENT PARTICLES UPON EXPOSURE TO CHEMICAL, THERMAL, PHOTOLYTIC OR LASER IRRADIATION MEANS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-03-21 US disclosed
EP-0654711-B1 Compositions for making structured color images and application thereof CIBA GEIGY AG (CH) 1999-06-02 EP disclosed
US-5871670-A Electroconductive composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-16 US disclosed
US-5830267-A Coloration of high molecular weight organic materials in the mass with soluble phthalocyanine precursors CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-03 US disclosed
EP-0782750-A1 NOVEL ELECTROCONDUCTIVE COMPOSITION Ciba SC Holding AG (CH) 1997-07-09 EP disclosed
EP-0742255-A1 Colouration of high molecular weight organic materials in the mass with soluble phthalocyanine precursors CIBA-GEIGY AG (CH) 1996-11-13 EP disclosed
WO-1996009629-A1 NOVEL ELECTROCONDUCTIVE COMPOSITION CIBA SPECIALTY CHEMICALS HOLDIING INC (CH) 1996-03-28 WO disclosed
EP-0654711-A1 Compositions for making structured color images and application thereof CIBA-GEIGY AG (CH) 1995-05-24 EP disclosed
JP-S62209117-A NOVEL COPOLYMER AND PRODUCTION THEREOF TSURUTA TEIJI 1987-09-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050006014-A1 Functionalized monomers for synthesis of rubbery polymers RDX, DPY30, COIL ALDH1A1 1516/4885TSHR 4018/4885ESR1 1503/4885
US-20040063884-A1 Functionalized monomers for synthesis of rubbery polymers RDX, DPY30, RIF1 ALDH1A1 1009/4885TSHR 3827/4885ESR1 1735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.