Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | P4HB | P07237 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544033 | 0.89 | ALDH1A1 (0.67) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1940052 | 0.83 | KMT2A (0.59) | KMT2AALDH1A1GAAHTTLMNA | |
| SCHEMBL7704838 | 0.83 | ALDH1A1 (0.67) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6911921 | 0.83 | ALDH1A1 (0.69) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7868868 | 0.81 | KMT2A (0.61) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9595885 | 0.81 | KMT2A (0.61) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7868867 | 0.81 | ALDH1A1 (0.65) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28141709 | 0.81 | KMT2A (0.61) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3062774 | 0.81 | ALDH1A1 (0.68) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8447060 | 0.81 | ALDH1A1 (0.67) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634948-B1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INST NAT SANTE RECH MED (FR) | 2025-09-17 | — | — | EP | disclosed |
| EP-3634949-B1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INST NAT SANTE RECH MED (FR) | 2025-03-19 | — | — | EP | disclosed |
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-10-24 | — | — | US | disclosed |
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-10-24 | — | — | US | disclosed |
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-10-24 | — | — | US | disclosed |
| US-11607419-B2 | Inhibitors of RAC1 and uses thereof for inducing bronchodilatation | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2023-03-21 | — | — | US | disclosed |
| WO-2018224563-A9 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2021-04-22 | — | — | WO | disclosed |
| WO-2018224563-A9 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2021-04-22 | — | — | WO | disclosed |
| US-20210077508-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | NANTES UNIVERSITE (FR) | 2021-03-18 | — | — | US | disclosed |
| EP-3634948-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | Institut National de la Sante et de la Recherche Medicale (INSERM) (FR) | 2020-04-15 | — | — | EP | disclosed |
| EP-3634949-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2020-04-15 | — | — | EP | disclosed |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | NANTES UNIVERSITE (FR) | 2020-03-26 | — | — | US | disclosed |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | NANTES UNIVERSITE (FR) | 2020-03-26 | — | — | US | disclosed |
| WO-2018224560-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-13 | — | — | WO | disclosed |
| WO-2018224563-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-13 | — | — | WO | disclosed |
| EP-3412651-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-12 | — | — | EP | disclosed |
| EP-3412652-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | RAC1, KRAS, CYRIB | KMT2A 3254/4885ALDH1A1 2069/4885CYP3A4 4103/4885 |
| US-11607419-B2 | Inhibitors of RAC1 and uses thereof for inducing bronchodilatation | RAC1, CYRIB, ARHGDIB | KMT2A 4243/4885ALDH1A1 2264/4885CYP3A4 2705/4885 |
| US-20210077508-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | RAC1, CYRIB, ARHGDIB | KMT2A 4243/4885ALDH1A1 2264/4885CYP3A4 2705/4885 |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | RAC1, KRAS, CYRIB | KMT2A 3254/4885ALDH1A1 2069/4885CYP3A4 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.