Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | CDC7 | O00311 | 2/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21024951 | 0.82 | IRAK4 (0.52) | MTORPIK3CAIRAK4LMNASMN1; SMN2 | |
| SCHEMBL18394735 | 0.82 | KDM4E (0.46) | ALDH1A1KDM4EMTORL3MBTL1PIK3CA | |
| SCHEMBL18394475 | 0.81 | USP2 (0.44) | ALDH1A1KDM4EMTORL3MBTL1RECQL | |
| SCHEMBL18395300 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EMTORL3MBTL1RECQL | |
| SCHEMBL29664456 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EMTORL3MBTL1RECQL | |
| SCHEMBL20022399 | 0.79 | CDC7 (0.62) | ALDH1A1KDM4ECDC7DBF4POLB | |
| SCHEMBL2080239 | 0.79 | MEN1 (0.54) | ALDH1A1KDM4ECDC7DBF4L3MBTL1 | |
| SCHEMBL289392 | 0.77 | CDC7 (0.60) | ALDH1A1KDM4ECDC7DBF4POLB | |
| SCHEMBL289684 | 0.77 | CDC7 (0.60) | ALDH1A1KDM4ECDC7DBF4POLB | |
| SCHEMBL18394360 | 0.77 | L3MBTL1 (0.46) | ALDH1A1KDM4EMTORL3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752598-B2 | Aryldiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-10752598-B2 | Aryldiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-10647711-B2 | Azepin-2-one derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-10647711-B2 | Azepin-2-one derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190152968-A1 | AZEPIN-2-ONE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2019-05-23 | — | — | US | disclosed |
| US-20190152968-A1 | AZEPIN-2-ONE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2019-05-23 | — | — | US | disclosed |
| WO-2018226801-A1 | ARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2018-12-13 | — | — | WO | disclosed |
| US-20180354912-A1 | ARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2018-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354912-A1 | ARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | AHR, FURIN, CYP3A5 | ALDH1A1 375/4885KDM4E 544/4885CDC7 4472/4885 |
| US-20190152968-A1 | AZEPIN-2-ONE DERIVATIVES AS RSV INHIBITORS | AZI2, FURIN, ACE2 | ALDH1A1 1328/4885KDM4E 892/4885CDC7 4202/4885 |
| US-10647711-B2 | Azepin-2-one derivatives as RSV inhibitors | AZI2, FURIN, ACE2 | ALDH1A1 1328/4885KDM4E 892/4885CDC7 4202/4885 |
| US-10752598-B2 | Aryldiazepine derivatives as RSV inhibitors | AHR, FURIN, CYP3A5 | ALDH1A1 375/4885KDM4E 544/4885CDC7 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.