Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395300 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EDGAT1SOAT1RXFP1 | |
| SCHEMBL18412891 | 0.85 | HTR2C (0.46) | ALDH1A1HSD17B10HTR2CPRKDCTP53 | |
| SCHEMBL18394360 | 0.81 | L3MBTL1 (0.46) | ALDH1A1KDM4EDGAT1SOAT1RXFP1 | |
| SCHEMBL20580211 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4ERXFP1PIK3CAHSD17B10 | |
| SCHEMBL18394620 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4ERXFP1PIK3CAHSD17B10 | |
| SCHEMBL20098503 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4ERXFP1PIK3CAHSD17B10 | |
| SCHEMBL18394735 | 0.77 | KDM4E (0.46) | ALDH1A1KDM4ERXFP1PIK3CAHSD17B10 | |
| SCHEMBL18394475 | 0.77 | USP2 (0.44) | ALDH1A1KDM4EPIK3CAHSD17B10L3MBTL1 | |
| SCHEMBL18394319 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4ERXFP1PIK3CAHSD17B10 | |
| SCHEMBL20867219 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4ERXFP1PIK3CAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386118-B | Combination pharmaceutical agents as RSV inhibitors | 英安塔制药有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-108200760-B | Benzodiazepine derivatives as RSV inhibitors | 英安塔制药有限公司 | 2022-04-01 | — | — | CN | disclosed |