Methane

Methane

SCHEMBL20580381

C.C=C(C(=O)OCCO)c1ccccc1.C=C(C(=O)OCCO)c1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
TDP1 Q9NUW8 4/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.44
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
SLC7A5 Q01650 1/20 0.38
RECQL P46063 1/20 0.38
MAPK1 P28482 3/20 0.38
KMT2A Q03164 2/20 0.38
HIF1A Q16665 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
TARBP2 Q15633 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1976801 0.98 GAA (0.46) GAATDP1ATMALDH1A1MAPT
SCHEMBL2376423 0.88 SMN1; SMN2 (0.46) GAATDP1ATMALDH1A1MAPT
SCHEMBL9738620 0.88 SMN1; SMN2 (0.46) GAATDP1ATMALDH1A1MAPT
SCHEMBL8093482 0.88 TARBP2 (0.46) GAAALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL597720 0.88 TDP1 (0.50) GAATDP1ATMALDH1A1MAPT
SCHEMBL12443036 0.85 TDP1 (0.51) GAATDP1ATMALDH1A1MAPT
SCHEMBL4912837 0.84 TDP1 (0.58) TDP1ATMALDH1A1MAPTLMNA
SCHEMBL27298398 0.83 TDP1 (0.47) TDP1ATMALDH1A1MAPTLMNA
SCHEMBL3795226 0.82 TDP1 (0.44) TDP1ATMALDH1A1MAPTLMNA
SCHEMBL4905507 0.82 LMNA (0.62) GAATDP1ATMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210108088-A1 COATING SYSTEM ELEMENTIS SPECIALTIES, INC. (US) 2021-04-15 US disclosed
US-10894886-B2 Coating system ELEMENTIS SPECIALTIES, INC. (US) 2021-01-19 US disclosed
EP-3638417-A1 COATING SYSTEM Elementis Specialties, Inc. (US) 2020-04-22 EP disclosed
WO-2018231920-A1 NAIL COLOR COATING SYSTEM ELEMENTIS SPECIALTIES, INC. (US) 2018-12-20 WO disclosed
WO-2018231922-A1 COATING SYSTEM ELEMENTIS SPECIALTIES, INC. (US) 2018-12-20 WO disclosed
WO-2018231927-A1 CLEAR COAT FORMULATIONS FOR USE OVER NAIL POLISH ELEMENTIS SPECIALTIES, INC. (US) 2018-12-20 WO disclosed
US-20180355185-A1 COATING SYSTEM ELEMENTIS SPECIALTIES, INC. (US) 2018-12-13 US disclosed
US-20180353421-A1 CLEAR COAT FORMULATIONS FOR USE OVER NAIL POLISH ELEMENTIS SPECIALTIES, INC. (US) 2018-12-13 US disclosed
US-20180353400-A1 NAIL COLOR COATING SYSTEM ELEMENTIS SPECIALTIES, INC. (US) 2018-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180353421-A1 CLEAR COAT FORMULATIONS FOR USE OVER NAIL POLISH PRKDC, POLR1C, PRKACG GAA 4086/4885TDP1 2616/4885ATM 3320/4885
US-20180353400-A1 NAIL COLOR COATING SYSTEM POLR1C, NACA, ETF1 GAA 4195/4885TDP1 2644/4885ATM 4368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.