Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.86 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5087908 | 1.00 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5087251 | 1.00 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL9743033 | 1.00 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5091757 | 0.97 | SLC22A1 (0.87) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5086680 | 0.97 | SLC22A1 (0.87) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL11307232 | 0.97 | SLC22A1 (0.87) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5088121 | 0.97 | SLC22A1 (0.87) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5092172 | 0.97 | SLC22A1 (0.87) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL22263498 | 0.97 | SLC22A1 (0.87) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL22263506 | 0.97 | SLC22A1 (0.87) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790132-B | Fluorine-containing aldehyde and preparation method thereof | 三明学院 | 2024-03-22 | — | — | CN | claimed |
| CN-111757874-B | Methods for preparing modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2024-03-08 | — | — | CN | claimed |
| US-7967999-B2 | Heat storage substance, heat storage agent, heat reservoir, heat transport medium, cold insulation agent, cold insulator, melting point control agent for heat storage agent and supercooling preventive agent for heat storage agent | JFE ENGINEERING CORPORATION (JP) | 2011-06-28 | — | — | US | claimed |
| US-20100234603-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | claimed |
| US-20100133464-A1 | Heat storage substance, heat storage agent, heat reservoir, heat transport medium, cold insulation agent, cold insulator, melting point control agent for heat storage agent, supercooling preventive agent for heat storage agent and method for producing main agent of heat storage agent heat transport medium, or cold insulation agent | JFE ENGINEERING CORPORATION (JP) | 2010-06-03 | — | — | US | claimed |
| EP-1921124-A1 | HEAT STORABLE SUBSTANCE, HEAT STORAGE AGENT, HEAT STORAGE MATERIAL, HEAT TRANSFER MEDIUM, LOW TEMPERATURE INSULATION AGENT, LOW TEMPERATURE INSULATION MATERIAL, MELTING POINT CONTROLLING AGENT FOR HEAT STORAGE AGENT, AGENT FOR PREVENTION OF OVERCOOLING FOR USE IN HEAT STORAGE AGENT, AND PROCESS FOR | JFE Engineering Corporation (JP) | 2008-05-14 | — | — | EP | claimed |
| CN-114790132-B | Fluorine-containing aldehyde and preparation method thereof | 三明学院 | 2024-03-22 | — | — | CN | disclosed |
| CN-111757874-B | Methods for preparing modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114790132-A | Fluorine-containing aldehyde and preparation method thereof | 三明学院 | 2022-07-26 | — | — | CN | disclosed |
| EP-3555102-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |
| US-10823477-B2 | Thermal energy storage member and storage container using the same, and refrigerator using the same | SHARP KABUSHIKI KAISHA (JP) | 2020-11-03 | — | — | US | disclosed |
| US-20200113181-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-16 | — | — | US | disclosed |
| EP-3555102-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2019-10-23 | — | — | EP | disclosed |
| US-20100133464-A1 | Heat storage substance, heat storage agent, heat reservoir, heat transport medium, cold insulation agent, cold insulator, melting point control agent for heat storage agent, supercooling preventive agent for heat storage agent and method for producing main agent of heat storage agent heat transport medium, or cold insulation agent | JFE ENGINEERING CORPORATION (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| EP-1921124-A1 | HEAT STORABLE SUBSTANCE, HEAT STORAGE AGENT, HEAT STORAGE MATERIAL, HEAT TRANSFER MEDIUM, LOW TEMPERATURE INSULATION AGENT, LOW TEMPERATURE INSULATION MATERIAL, MELTING POINT CONTROLLING AGENT FOR HEAT STORAGE AGENT, AGENT FOR PREVENTION OF OVERCOOLING FOR USE IN HEAT STORAGE AGENT, AND PROCESS FOR | JFE Engineering Corporation (JP) | 2008-05-14 | — | — | EP | disclosed |
| EP-1921124-A1 | HEAT STORABLE SUBSTANCE, HEAT STORAGE AGENT, HEAT STORAGE MATERIAL, HEAT TRANSFER MEDIUM, LOW TEMPERATURE INSULATION AGENT, LOW TEMPERATURE INSULATION MATERIAL, MELTING POINT CONTROLLING AGENT FOR HEAT STORAGE AGENT, AGENT FOR PREVENTION OF OVERCOOLING FOR USE IN HEAT STORAGE AGENT, AND PROCESS FOR | JFE Engineering Corporation (JP) | 2008-05-14 | — | — | EP | disclosed |
| JP-2007161893-A | HEAT-STORAGE AGENT, HEAT-TRANSFER MEDIUM, MELTING POINT-CONTROLLING AGENT FOR HEAT-STORAGE AGENT, AGENT FOR PREVENTION OF OVERCOOLING FOR USE IN HEAT-STORAGE AGENT, METHOD FOR PRODUCING THE HEAT-STORAGE AGENT OR MAIN INGREDIENT OF THE HEAT-TRANSFER MEDIUM AND TRI-n-BUTYL-n-PENTYLAMMONIUM CHLORIDE HYDRATE | JFE ENGINEERING KK | 2007-06-28 | — | — | JP | disclosed |
| US-4009116-A | Process of preparing substantially organic waste liquids containing radioactive or toxic substances for safe, non-pollutive handling, transportation and permanent storage | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-22 | — | — | US | disclosed |
| US-3960762-A | Production of absorbents | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200113181-A1 | HERBICIDAL COMPOUNDS | DDT, DHRS9, H1-10 | SLC22A1 2105/4885SLC22A2 2501/4885ALDH1A1 130/4885 |
| US-20100234603-A1 | Process for Making Substituted Aryl Sulfone Intermediates | SULT1A1, SULT1E1, STS | SLC22A1 3643/4885SLC22A2 3768/4885ALDH1A1 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.