Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.90 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL1270969 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL29822171 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL2774 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL32661377 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL29349552 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL3848658 | 0.92 | ALDH1A1 (0.85) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL2313500 | 0.92 | ALDH1A1 (0.85) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL23202414 | 0.92 | ALDH1A1 (0.94) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL5422407 | 0.92 | ALDH1A1 (0.94) | ALDH1A1MAPTHTTKDM4ECASP1 | |
| Quinoline SCHEMBL6381814 | 0.92 | ALDH1A1 (0.94) | ALDH1A1MAPTHTTKDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184681-A | Spiro 1,2, 4-triazole carbene metal complex, intermediate, preparation method and application thereof | 浙江工业大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-114349656-B | Preparation method of hydrazide compound | 赣南师范大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-114349656-A | Preparation method of hydrazide compound | 赣南师范大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-112300173-B | Nitrogen-containing polycyclic compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-112300173-A | Nitrogen-containing polycyclic compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-104704366-B | Azaindole quinoline-the cyanine dye and its bioconjugates of hydroxamic acid substitution | 贝克顿·迪金森公司 | 2018-06-19 | — | — | CN | disclosed |
| EP-2912464-A1 | HYDROXAMATE SUBSTITUTED AZAINDOLINE-CYANINE DYES AND BIOCONJUGATES OF THE SAME | Becton Dickinson and Company (US) | 2015-09-02 | — | — | EP | disclosed |
| CN-104704366-A | Hydroxamate substituted azaindoline-cyanine dyes and bioconjugates of the same | BECTON DICKINSON CO | 2015-06-10 | — | — | CN | disclosed |
| WO-2014066552-A1 | HYDROXAMATE SUBSTITUTED AZAINDOLINE-CYANINE DYES AND BIOCONJUGATES OF THE SAME | BECTON, DICKINSON AND COMPANY (US) | 2014-05-01 | — | — | WO | disclosed |
| CN-103335880-A | Method for separating and enriching carbadox and chlorpromazine in water | CHINESE RES ACAD ENV SCIENCES | 2013-10-02 | — | — | CN | disclosed |
| EP-2201070-A2 | AZO QUINOLINIUM COMPOUNDS COMPRISING A DISULPHIDE/THIOL UNIT, COMPOSITIONS CONTAINING SAME, PROCESS FOR DYEING KERATIN FIBRES AND DEVICE | L'Oreal (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009034059-A2 | AZO QUINOLINIUM COMPOUNDS COMPRISING A DISULPHIDE/THIOL UNIT, COMPOSITIONS CONTAINING SAME, PROCESS FOR DYEING KERATIN FIBRES AND DEVICE | L'OREAL (FR) | 2009-03-19 | — | — | WO | disclosed |
| CN-1204216-C | Anti-alkali smelting combined epoxy modified powder paint | INST METAL RES CHINESE ACAD SC (CN) | 2005-06-01 | — | — | CN | disclosed |
| CN-1511905-A | Anti-alkali smelting combined epoxy modified powder paint | 中国科学院金属研究所 | 2004-07-14 | — | — | CN | disclosed |
| US-20040105614-A1 | Optical switching element and photoaddressable display medium using the same | FUJI XEROX CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| US-20030219377-A1 | Compounds and methods for diagnosing and treating amyloid-related conditions | PHARMACIA & UPJOHN COMPANY | 2003-11-27 | — | — | US | disclosed |
| US-6589504-B1 | Binding or aggregating fibrils with radiolabeled quinoline-hydrazone compound | PHARMACIA & UPJOHN COMPANY | 2003-07-08 | — | — | US | disclosed |
| EP-1318982-A1 | COMPOUNDS AND METHODS FOR DIAGNOSING AND TREATING AMYLOID-RELATED CONDITIONS | PHARMACIA & UPJOHN COMPANY (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024652-A1 | COMPOUNDS AND METHODS FOR DIAGNOSING AND TREATING AMYLOID-RELATED CONDITIONS | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |
| US-4407803-A | ANTIASTHMA, ANTI-RHEUMATOID ARTHRITIS | ABBOTT LABORATORIES (US) | 1983-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030219377-A1 | Compounds and methods for diagnosing and treating amyloid-related conditions | APP, IAPP, HTT | ALDH1A1 694/4885MAPT 13/4885HTT 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.