SCHEMBL2058710

SCHEMBL2058710

COC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.74
LAP3 P28838 1/20 0.62
PPARG P37231 4/20 0.60
LNPEP Q9UIQ6 3/20 0.58
MAOB P27338 1/20 0.56
PPARA Q07869 2/20 0.56
FFAR1 O14842 1/20 0.55
FFAR4 Q5NUL3 1/20 0.55
EPOR P19235 1/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6162332 1.00 LTA4H (0.74) LTA4HLAP3PPARGLNPEPMAOB
SCHEMBL7921142 1.00 LTA4H (0.74) LTA4HLAP3PPARGLNPEPMAOB
Hydrochloric Acid SCHEMBL3497991 0.99 LTA4H (0.73) LTA4HLAP3PPARGLNPEPMAOB
Hydrochloric Acid SCHEMBL3499496 0.99 LTA4H (0.73) LTA4HLAP3PPARGLNPEPMAOB
Hydrochloric Acid SCHEMBL3497988 0.99 LTA4H (0.73) LTA4HLAP3PPARGLNPEPMAOB
Phenylalanine Methyl Ester SCHEMBL28633098 0.96 LTA4H (0.70) LTA4HLAP3PPARGLNPEPPPARA
Butylamine SCHEMBL8391542 0.91 LTA4H (0.63) LTA4HLAP3PPARGLNPEPEPOR
SCHEMBL16607620 0.90 LTA4H (0.67) LTA4HLAP3PPARGLNPEPMAOB
SCHEMBL6561218 0.89 LTA4H (0.73) LTA4HLAP3PPARGLNPEPMAOB
SCHEMBL1855604 0.89 LTA4H (0.73) LTA4HLAP3PPARGLNPEPMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
EP-4551566-A1 NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS Les Laboratoires Servier (FR) 2025-05-14 EP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
WO-2024044549-A1 VHH ANTIBODY CONJUGATES Abdera Therapeutics Inc. (US) 2024-02-29 WO disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
WO-2024008941-A1 NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS LES LABORATOIRES SERVIER (FR) 2024-01-11 WO disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
CN-102659617-B L-tyrosine derivative, medicine compound and application thereof UNIV TIANJIN MEDICAL 2014-05-21 CN disclosed
WO-1999006433-A1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS, INC. (US) 1999-02-11 WO disclosed
EP-0888317-A1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LIMITED (GB) 1999-01-07 EP disclosed
WO-1997031907-A1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LIMITED (GB) 1997-09-04 WO disclosed
EP-0770063-A1 TECHNETIUM-SULPHONAMIDE COMPLEXES, THEIR USE, PHARMACEUTICAL AGENTS CONTAINING THEM, AND PROCESS FOR PRODUCING THE COMPLEXES AND AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1997-05-02 EP disclosed
WO-1996022962-A9 BUTYRYL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME 1996-10-03 WO disclosed
WO-1996022962-A1 BUTYRYL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1996-08-01 WO disclosed
WO-1996002500-A1 TECHNETIUM-SULPHONAMIDE COMPLEXES, THEIR USE, PHARMACEUTICAL AGENTS CONTAINING THEM, AND PROCESS FOR PRODUCING THE COMPLEXES AND AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1996-02-01 WO disclosed
CN-1112364-A Piperazine derivatives and salts thereof OTSUKA PHARMA CO LTD (JP) 1995-11-22 CN disclosed
US-4574079-A Radiolabeled angiotensin converting enzyme inhibitors for radiolabeling mammalian organ sites BOSTON UNIVERSITY, A NOT FOR PROFIT CORP 1986-03-04 US disclosed
EP-0030845-A2 Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them ELI LILLY AND COMPANY (US) 1981-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX LTA4H 3870/4885LAP3 2378/4885PPARG 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.