Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727046 | 1.00 | ALDH1A1 (0.52) | ALDH1A1RXRARXRBPDPK1MAPT | |
| Water SCHEMBL9342313 | 0.97 | ALDH1A1 (0.50) | ALDH1A1RXRARXRBPDPK1MAPT | |
| SCHEMBL20587670 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNATP53TSHR | |
| SCHEMBL68148 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNATP53TSHR | |
| SCHEMBL23630426 | 0.89 | TSHR (0.60) | RXRARXRBBCL2L1BADTP53 | |
| SCHEMBL2902010 | 0.89 | CES2 (0.56) | ALDH1A1RXRARXRBMAPTLMNA | |
| SCHEMBL14416 | 0.89 | SMN1; SMN2 (0.60) | ALDH1A1MAPTSMN1; SMN2RAB9AMEN1 | |
| Biphenyl SCHEMBL28809192 | 0.89 | SMN1; SMN2 (0.60) | ALDH1A1MAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL10348291 | 0.89 | TSHR (0.60) | RXRARXRBBCL2L1BADTP53 | |
| SCHEMBL8723556 | 0.89 | SMN1; SMN2 (0.60) | ALDH1A1MAPTSMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762869-A | BLOCK POLYETHERS WITH SULFONES AND CARBONYLS | BASF AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0274098-A2 | Process for producing polymers in particle shape | BASF Aktiengesellschaft (DE) | 1988-07-13 | — | — | EP | disclosed |
| EP-0243831-A2 | High-temperature-resistant moulding composition | BASF Aktiengesellschaft (DE) | 1987-11-04 | — | — | EP | disclosed |