Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058928 | 1.00 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL28177818 | 1.00 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL17914173 | 1.00 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL2058987 | 1.00 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL2058434 | 1.00 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL2058893 | 1.00 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| Water SCHEMBL28491651 | 0.98 | ALDH1A1 (0.52) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL4601930 | 0.98 | ALDH1A1 (0.56) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL11782469 | 0.93 | LMNA (0.50) | ALDH1A1EPHX2CES2CES1 | |
| SCHEMBL8046344 | 0.91 | ALDH1A1 (0.65) | ALDH1A1EPHX2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968750-B2 | Process for producing nitrogen-containing compounds | KAO CORPORATION (JP) | 2011-06-28 | — | — | US | claimed |
| EP-1254099-B1 | PROCESS FOR THE PRODUCTION OF ANHYDROUS FORMIC ACID | BASF AG (DE) | 2006-04-26 | — | — | EP | claimed |
| US-11814391-B2 | Macrocyclic compounds for the treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814391-B2 | Macrocyclic compounds for the treatment of medical disorders | CFD, TFPI, CFH | ALDH1A1 4659/4885EPHX2 2420/4885CES2 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.