SCHEMBL5425916

SCHEMBL5425916

CCN1C(=O)C(=CC=C2CCCN2C)C(=O)N(CC)C1=S

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.64
KMT2A Q03164 11/20 0.64
MAPT P10636 10/20 0.64
ALDH1A1 P00352 10/20 0.64
RAB9A P51151 5/20 0.64
NPC1 O15118 3/20 0.64
IDE P14735 2/20 0.64
KDM4E B2RXH2 2/20 0.64
GAA P10253 4/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
PSMD14 O00487 2/20 0.56
LMNA P02545 2/20 0.46
USP2 O75604 1/20 0.46
POLB P06746 3/20 0.43
HPGD P15428 2/20 0.43
HTT P42858 2/20 0.43
THRB P10828 1/20 0.43
MDM2 Q00987 1/20 0.43
KDM4C Q9H3R0 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14489574 1.00 MEN1 (0.64) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL19240011 0.88 MEN1 (0.59) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL14582093 0.77 ALDH1A1 (0.63) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL25477347 0.76 MEN1 (0.46) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL2058993 0.75 KMT2A (0.56) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL14269386 0.75 KMT2A (0.56) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL2058995 0.75 KMT2A (0.56) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL13026074 0.72 MAPT (1.00) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL6741916 0.72 MAPT (1.00) MEN1KMT2AMAPTALDH1A1RAB9A
SCHEMBL6741919 0.72 MAPT (1.00) MEN1KMT2AMAPTALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148556-A1 Photosensitive composition for volume hologram recording DAI NIPPON PRINTING CO., LTD. (JP) 2007-06-28 US claimed
US-20070148556-A1 Photosensitive composition for volume hologram recording DAI NIPPON PRINTING CO., LTD. (JP) 2007-06-28 US disclosed