SCHEMBL25477347

SCHEMBL25477347

CC(C)CN1C(=O)C(=C/C=C2\CCCN2C)C(=O)N(CC(C)C)C1=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
MAPT P10636 4/20 0.46
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 4/20 0.46
RAB9A P51151 3/20 0.46
IDE P14735 2/20 0.46
KDM4E B2RXH2 2/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 3/20 0.45
PSMD14 O00487 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
EP300 Q09472 4/20 0.41
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
PIK3CD O00329 2/20 0.37
BRD4 O60885 1/20 0.36
BRD2 P25440 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19240011 0.84 MEN1 (0.59) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL2058993 0.77 KMT2A (0.56) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL2058995 0.77 KMT2A (0.56) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL14269386 0.77 KMT2A (0.56) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL5425916 0.76 MEN1 (0.64) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL14489574 0.76 MEN1 (0.64) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL19240021 0.69 MAPT (0.47) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL19240048 0.67 MEN1 (0.72) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL19240010 0.66 ALDH1A1 (0.47) MEN1MAPTKMT2AALDH1A1RAB9A
SCHEMBL19038912 0.66 ALDH1A1 (0.47) MEN1MAPTKMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230258853-A1 OPTICAL FILTER AGC Inc. (JP) 2023-08-17 US disclosed
US-20230258853-A1 OPTICAL FILTER AGC Inc. (JP) 2023-08-17 US disclosed
US-20230145740-A1 OPTICAL FILTER AGC Inc. (JP) 2023-05-11 US disclosed
US-20230145740-A1 OPTICAL FILTER AGC Inc. (JP) 2023-05-11 US disclosed