Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20590895 | 0.82 | CYP4F2 (0.62) | CYP4F2CYP4A11ATRP4HTMHRH3 | |
| SCHEMBL22070515 | 0.82 | CYP4F2 (0.51) | CYP4F2CYP4A11FGFR1FGFR2FGFR4 | |
| SCHEMBL20590870 | 0.80 | CYP4F2 (0.79) | CYP4F2CYP4A11ATRP4HTM | |
| SCHEMBL19277419 | 0.79 | CYP4F2 (0.43) | CYP4F2CYP4A11FGFR1FGFR2FGFR4 | |
| SCHEMBL29689591 | 0.79 | KDM5B (0.44) | CYP4F2CYP4A11FGFR1FGFR2FGFR4 | |
| SCHEMBL31434638 | 0.78 | KDM5B (0.43) | CYP4F2CYP4A11FGFR1FGFR2FGFR4 | |
| SCHEMBL31434739 | 0.78 | FLT3 (0.45) | CYP4F2CYP4A11FGFR1FGFR2FGFR4 | |
| SCHEMBL20590847 | 0.78 | CYP4F2 (0.57) | CYP4F2CYP4A11ATRP4HTM | |
| SCHEMBL28545279 | 0.78 | MCL1 (0.46) | CYP4F2CYP4A11FGFR1FGFR2FGFR4 | |
| SCHEMBL30895651 | 0.77 | KDM5B (0.42) | CYP4F2CYP4A11FGFR1FGFR2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040062-A1 | AZOLE-SUBSTITUTED PYRIDINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2021-02-11 | — | — | US | disclosed |
| EP-3418276-A1 | AZOLE-SUBSTITUTED PYRIDINE COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2018-12-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040062-A1 | AZOLE-SUBSTITUTED PYRIDINE COMPOUND | CYP2F1, CYP21A2, CYP11B1 | CYP4F2 8/4885CYP4A11 13/4885FGFR1 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.