Acrylamide

Acrylamide

SCHEMBL205957

C=C(CCCl)C(=O)OCCN(C)C.C=CC(N)=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRM3 P20309 1/20 0.38
CHRNA4 P43681 1/20 0.38
DNM1 Q05193 1/20 0.35
PHLPP2 Q6ZVD8 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
FGFR4 P22455 1/20 0.31
BCHE P06276 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL253219 0.89 CHRM1 (0.46) CHRM2CHRM4CHRM5CHRM1CHRNB2
Acrylamide SCHEMBL205773 0.88 CHRM2 (0.40) CHRM2CHRM4CHRM5CHRM1CHRNB2
Acrylamide SCHEMBL205958 0.81 THRB (0.41) CHRM2CHRM4CHRM5CHRM1CHRNB2
Acrylamide SCHEMBL317113 0.80 THRB (0.43) CHRM2CHRM4CHRM5CHRM1CHRNB2
Acrylamide SCHEMBL11030958 0.79 THRB (0.42) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL27545231 0.78 CHRM1 (0.50) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL16429854 0.78 DNM1 (0.47) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL16429931 0.78 DNM1 (0.47) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL16429852 0.78 DNM1 (0.47) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL16429738 0.78 DNM1 (0.47) CHRM2CHRM4CHRM5CHRM1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2188448-B2 CONTROLLABLE FILLER PREFLOCULATION USING A DUAL POLYMER SYSTEM NALCO CO (US) 2022-05-25 EP disclosed
EP-2430236-B1 CONTROLLABLE FILLER PREFLOCULATION USING A DUAL POLYMER SYSTEM NALCO CO (US) 2021-06-30 EP disclosed
EP-2188448-B1 CONTROLLABLE FILLER PREFLOCULATION USING A DUAL POLYMER SYSTEM NALCO CO (US) 2016-08-17 EP disclosed
US-8747617-B2 Controllable filler prefloculation using a dual polymer system NALCO COMPANY (US) 2014-06-10 US disclosed
US-20120199304-A1 CONTROLLABLE FILLER PREFLOCULATION USING A DUAL POLYMER SYSTEM NALCO COMPANY 2012-08-09 US disclosed
US-8172983-B2 Controllable filler prefloculation using a dual polymer system NALCO COMPANY (US) 2012-05-08 US disclosed
US-8088213-B2 Controllable filler prefloculation using a dual polymer system NALCO COMPANY (US) 2012-01-03 US disclosed
US-20090267258-A1 CONTROLLABLE FILLER PREFLOCULATION USING A DUAL POLYMER SYSTEM NALCO COMPANY 2009-10-29 US disclosed
US-20090065162-A1 CONTROLLABLE FILLER PREFLOCULATION USING A DUAL POLYMER SYSTEM ECOLAB USA INC. 2009-03-12 US disclosed