Acrylamide

Acrylamide

SCHEMBL205958

C=C(C)C(=O)OCCN(C)C.C=CC(N)=O.CCl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRM3 P20309 1/20 0.41
CHRNA4 P43681 1/20 0.41
TSHR P16473 4/20 0.40
PHLPP2 Q6ZVD8 1/20 0.36
ALDH1A1 P00352 4/20 0.34
FGFR4 P22455 1/20 0.34
DNM1 Q05193 1/20 0.34
BCHE P06276 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL317113 0.97 THRB (0.43) THRBCHRM2CHRM4CHRM5CHRM1
Acrylamide SCHEMBL11030958 0.95 THRB (0.42) THRBCHRM2CHRM4CHRM5CHRM1
Acrylamide SCHEMBL11133423 0.91 THRB (0.39) THRBCHRM2CHRM4CHRM5CHRM1
Chloromethane SCHEMBL127392 0.88 CHRM2 (0.50) THRBCHRM2CHRM4CHRM5CHRM1
Acrylamide SCHEMBL6936330 0.88 TSHR (0.47) THRBCHRM2CHRM4CHRM5CHRM1
Acrylamide SCHEMBL10524522 0.87 THRB (0.36) THRBCHRM2CHRM4CHRM5CHRM1
SCHEMBL29263179 0.87 THRB (0.46) THRBCHRM2CHRM4CHRM5CHRM1
Chloromethane SCHEMBL28392740 0.87 THRB (0.48) THRBCHRM2CHRM4CHRM5CHRM1
Chloromethane SCHEMBL28961621 0.87 THRB (0.48) THRBCHRM2CHRM4CHRM5CHRM1
Chloromethane SCHEMBL28164387 0.87 THRB (0.48) THRBCHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8512685-B2 Hair lightening composition containing polymer film KAO USA INC. (US) 2013-08-20 US claimed
EP-2496212-A2 HAIR LIGHTENTING COMPOSITION CONTAINING POLYMER FILM KAO Brands Company (US) 2012-09-12 EP claimed
WO-2011056825-A2 HAIR LIGHTENTING COMPOSITION CONTAINING POLYMER FILM KAO BRANDS COMPANY (US) 2011-05-12 WO claimed
US-20110104090-A1 Hair Lightening Composition Containing Polymer Film KAO BRANDS COMPANY (US) 2011-05-05 US claimed
EP-4355726-A1 POLYMERIC FATTY ACID SALT COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID-BASED SUBSTRATES, ESPECIALLY HAIR Momentive Performance Materials GmbH (DE) 2024-04-24 EP disclosed
EP-4240316-A1 STYLING SHAMPOO COMPOSITIONS BASF SE (DE) 2023-09-13 EP disclosed
US-20230022614-A1 POLYMERIC FATTY ACID SALT COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID-BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MAT GMBH (DE) 2023-01-26 US disclosed
WO-2022263525-A1 POLYMERIC FATTY ACID SALT COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID-BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2022-12-22 WO disclosed
EP-2188448-B2 CONTROLLABLE FILLER PREFLOCULATION USING A DUAL POLYMER SYSTEM NALCO CO (US) 2022-05-25 EP disclosed
WO-2022096243-A1 STYLING SHAMPOO COMPOSITIONS BASF SE (DE) 2022-05-12 WO disclosed
EP-2430236-B1 CONTROLLABLE FILLER PREFLOCULATION USING A DUAL POLYMER SYSTEM NALCO CO (US) 2021-06-30 EP disclosed
US-10702475-B2 Liposome containing compositions and their use in personal care and food products RIGG RICHARD (US) 2020-07-07 US disclosed
WO-2003106766-A1 METHOD OF DEWATERING PULP ONDEO NALCO COMPANY (US) 2003-12-24 WO disclosed
EP-0176757-B1 PREPARATION OF WATER SOLUBLE CATIONIC POLYMER AND PRODUCT POLYPURE INC. (US) 1990-11-07 EP disclosed
US-4783513-A Novel water soluble cationic acrylamide polymers having relatively uniform cationic quaternary amine functional unit distribution ALLIED-SIGNAL INC. (US) 1988-11-08 US disclosed
US-4668747-A Preparation of water soluble cationic acrylamide polymer and product using weak acid to adjust pH ALLIED CORPORATION (US) 1987-05-26 US disclosed
EP-0176757-A2 Preparation of water soluble cationic polymer and product POLYPURE INC. (US) 1986-04-09 EP disclosed
US-4421855-A CATIONIC ACRYLAMIDE-BASED POLYMER GEL NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1983-12-20 US disclosed
US-4339371-A High concentration water-soluble polymers in water-in-oil emulsions AMERICAN CYANAMID COMPANY (US) 1982-07-13 US disclosed
EP-0049766-A1 High concentration water soluble polymers as water-in-oil emulsions AMERICAN CYANAMID COMPANY (US) 1982-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022614-A1 POLYMERIC FATTY ACID SALT COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID-BASED SUBSTRATES, ESPECIALLY HAIR DAO, ELOVL3, ELOVL6 THRB 2796/4885CHRM2 4736/4885CHRM4 4569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.