Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS2 | Q96GW9 | 9/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20596159 | 0.91 | MARS2 (0.56) | MARS2 | |
| SCHEMBL20595924 | 0.88 | MARS2 (0.66) | MARS2 | |
| SCHEMBL23391548 | 0.88 | MARS2 (0.40) | MARS2P2RX3EGFRKDM4E | |
| SCHEMBL30145327 | 0.88 | MARS2 (0.40) | MARS2P2RX3EGFRKDM4E | |
| SCHEMBL20595966 | 0.82 | MARS2 (0.77) | MARS2P2RX3EGFR | |
| SCHEMBL20596079 | 0.82 | MARS2 (0.68) | MARS2 | |
| SCHEMBL30145277 | 0.79 | MARS2 (0.40) | MARS2P2RX3 | |
| SCHEMBL23391444 | 0.79 | MARS2 (0.40) | MARS2P2RX3 | |
| SCHEMBL20595831 | 0.79 | MARS2 (0.51) | MARS2 | |
| SCHEMBL23419242 | 0.77 | MARS2 (0.48) | MARS2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018237349-A1 | INHIBITORS OF TYPED 1 METHIONYL-TRNA SYNTHETASE AND METHODS OF USING THEM | UNIVERSITY OF WASHINGTON (US) | 2018-12-27 | — | — | WO | claimed |