Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS2 | Q96GW9 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23391548 | 1.00 | MARS2 (0.40) | MARS2EGFRKDM4EP2RX3CHEK2 | |
| SCHEMBL23391444 | 0.92 | MARS2 (0.40) | MARS2P2RX3CHEK2 | |
| SCHEMBL30145277 | 0.92 | MARS2 (0.40) | MARS2P2RX3CHEK2 | |
| SCHEMBL23419242 | 0.89 | MARS2 (0.48) | MARS2P2RX3CHEK2 | |
| SCHEMBL20596045 | 0.88 | MARS2 (0.54) | MARS2EGFRKDM4EP2RX3 | |
| SCHEMBL23419650 | 0.83 | MARS2 (0.51) | MARS2P2RX3 | |
| SCHEMBL20596159 | 0.78 | MARS2 (0.56) | MARS2CHEK2 | |
| SCHEMBL20595924 | 0.76 | MARS2 (0.66) | MARS2CHEK2 | |
| SCHEMBL23391426 | 0.73 | MARS2 (0.49) | MARS2P2RX3CHEK2 | |
| SCHEMBL30145253 | 0.73 | MARS2 (0.49) | MARS2P2RX3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584744-B2 | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them | UNIVERSITY OF WASHINGTON (US) | 2023-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584744-B2 | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them | AARS1, EMG1, GARS1 | MARS2 12/4885EGFR 4095/4885KDM4E 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.