Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | FPR1 | P21462 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20596644 | 0.79 | KDM4E (0.41) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL20596642 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL20595976 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL20596634 | 0.75 | LMNA (0.40) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL20596633 | 0.72 | GAA (0.47) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL23391613 | 0.71 | GAA (0.46) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL20595928 | 0.67 | KDM4E (0.43) | SMN1; SMN2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL20596629 | 0.67 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7319485 | 0.67 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL16278345 | 0.65 | KDM4E (0.42) | SMN1; SMN2KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018237349-A1 | INHIBITORS OF TYPED 1 METHIONYL-TRNA SYNTHETASE AND METHODS OF USING THEM | UNIVERSITY OF WASHINGTON (US) | 2018-12-27 | — | — | WO | disclosed |