Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451410 | 0.78 | HRH3 (0.33) | CA2 | |
| SCHEMBL16324836 | 0.68 | — | — | |
| SCHEMBL27285784 | 0.67 | CA2 (0.44) | CA2 | |
| SCHEMBL20772222 | 0.67 | PARP1 (0.41) | — | |
| SCHEMBL2921045 | 0.66 | TRPV4 (0.32) | — | |
| SCHEMBL17196352 | 0.60 | KDM4E (0.33) | — | |
| SCHEMBL22775171 | 0.55 | AR (0.44) | — | |
| SCHEMBL27285661 | 0.55 | PTGS2 (0.39) | — | |
| Sulfuric Acid SCHEMBL563263 | 0.54 | KMT2A (0.44) | CA2 | |
| SCHEMBL22589949 | 0.54 | HRH3 (0.49) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645516-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | Janssen Pharmaceutica NV (BE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019001420-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-03 | — | — | WO | disclosed |