SCHEMBL20599883

SCHEMBL20599883

OCCCN1CCC[C@H]1C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
DUT P33316 5/20 0.43
CYP2J2 P51589 2/20 0.41
NR1H4 Q96RI1 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HRH1 P35367 3/20 0.40
CYP2D6 P10635 2/20 0.40
SCN1A P35498 2/20 0.40
SCN2A Q99250 2/20 0.40
SCN3A Q9NY46 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CHRM3 P20309 3/20 0.39
SIGMAR1 Q99720 2/20 0.39
TMEM97 Q5BJF2 1/20 0.39
CHRM2 P08172 2/20 0.39
CHRM4 P08173 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20600150 1.00 LMNA (0.49) LMNAATML3MBTL1DUTCYP2J2
SCHEMBL6264165 0.92 LMNA (0.44) LMNAATML3MBTL1DUTCYP2J2
SCHEMBL8477470 0.87 LMNA (0.51) LMNAATML3MBTL1DUTCYP2J2
SCHEMBL8481946 0.87 LMNA (0.51) LMNAATML3MBTL1DUTCYP2J2
SCHEMBL8477474 0.87 LMNA (0.51) LMNAATML3MBTL1DUTCYP2J2
SCHEMBL8342637 0.84 LMNA (0.53) LMNAATML3MBTL1DUTHRH1
SCHEMBL8343216 0.84 LMNA (0.53) LMNAATML3MBTL1DUTHRH1
SCHEMBL8339348 0.84 LMNA (0.53) LMNAATML3MBTL1DUTHRH1
SCHEMBL8336623 0.81 LMNA (0.56) LMNAATML3MBTL1DUTHRH1
SCHEMBL8339280 0.81 LMNA (0.56) LMNAATML3MBTL1DUTHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019001712-A1 NEW TRIDENTATE POLYMERIZATION CATALYSTS GEORG-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS (DE) 2019-01-03 WO disclosed