Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878921 | 0.84 | SMN1; SMN2 (0.67) | TSHRGPR84SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1287276 | 0.79 | SMN1; SMN2 (0.69) | YTHDC1GPR84SMN1; SMN2TYMPTP53 | |
| SCHEMBL20599921 | 0.77 | SMN1; SMN2 (0.57) | TSHRGPR84SMN1; SMN2TYMPHSD17B10 | |
| SCHEMBL21234494 | 0.76 | UNG (0.55) | GPR84TYMPUNG | |
| Dimethylamine SCHEMBL27691701 | 0.75 | SMN1; SMN2 (0.63) | YTHDC1GPR84SMN1; SMN2TYMPTP53 | |
| SCHEMBL20625702 | 0.74 | TDP1 (0.53) | GPR84SMN1; SMN2ALDH1A1UNGRAB9A | |
| SCHEMBL14426642 | 0.73 | RAB9A (0.72) | TSHRYTHDC1GPR84SMN1; SMN2TYMP | |
| SCHEMBL20625637 | 0.72 | GPR84 (0.53) | TSHRGPR84SMN1; SMN2HSD17B10UNG | |
| SCHEMBL4625744 | 0.72 | SMN1; SMN2 (0.56) | TSHRYTHDC1GPR84SMN1; SMN2TYMP | |
| SCHEMBL9222745 | 0.71 | SMN1; SMN2 (0.41) | TSHRYTHDC1GPR84SMN1; SMN2TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019002407-A1 | PROCESS FOR THE PREPARATION OF TIPIRACIL HYDROCHLORIDE | AMNEAL PHARMACEUTICALS COMPANY GMBH (CH) | 2019-01-03 | — | — | WO | disclosed |