Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | TYMP | P19971 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | UNG | P13051 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL27691701 | 0.95 | SMN1; SMN2 (0.63) | SMN1; SMN2YTHDC1GPR84RAB9ADAO | |
| SCHEMBL14426642 | 0.82 | RAB9A (0.72) | SMN1; SMN2YTHDC1GPR84RAB9ATYMP | |
| Benzylthiouracil SCHEMBL815137 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2GPR84DAOPARP1ALDH1A1 | |
| SCHEMBL14123282 | 0.80 | HRH4 (0.51) | SMN1; SMN2YTHDC1RAB9ADAOALDH1A1 | |
| SCHEMBL14917577 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2GPR84DAOPARP1HSD17B10 | |
| SCHEMBL20599951 | 0.79 | TSHR (0.50) | SMN1; SMN2YTHDC1GPR84RAB9ADAO | |
| SCHEMBL17206126 | 0.78 | GPR84 (0.73) | SMN1; SMN2GPR84 | |
| Diphenylmethane SCHEMBL10711103 | 0.77 | CALM1 (0.63) | SMN1; SMN2DAOTYMPPARP1HSD17B10 | |
| SCHEMBL6613866 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2GPR84DAOPARP1HCAR2 | |
| SCHEMBL13757285 | 0.74 | DAO (0.49) | SMN1; SMN2DAOTYMPALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001789-B1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE FOR A SIMULATNEAOUS, SEPARATED OR TIME-SPREADED THERAPEUTIC USE | SOD CONSEILS RECH APPLIC (FR) | 2002-11-06 | — | — | EP | claimed |
| EP-1001789-A1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999007384-A1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-02-18 | — | — | WO | claimed |
| WO-2024137865-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| EP-4262986-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | Gossamer Bio Services, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES INC (US) | 2023-08-31 | — | — | US | disclosed |
| WO-2023122772-A1 | OXIME DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122777-A1 | OXIME DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022133083-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| CN-102838549-A | New class of 1,5,6-substituted pyrimidine derivatives with anti-HIV virus effects | UNIV BEIJING | 2012-12-26 | — | — | CN | disclosed |
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |
| US-20040171652-A1 | Antiviral and spermicidal contraceptives; 2-thiourea pyridinyl derivative containing compositions | PARKER HUGHES INSTITUTE | 2004-09-02 | — | — | US | disclosed |
| US-6774139-B1 | CONTRACEPTIVES | PARKER HUGHES INSTITUTE | 2004-08-10 | — | — | US | disclosed |
| EP-1001789-B1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE FOR A SIMULATNEAOUS, SEPARATED OR TIME-SPREADED THERAPEUTIC USE | SOD CONSEILS RECH APPLIC (FR) | 2002-11-06 | — | — | EP | disclosed |
| EP-1001789-B1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE FOR A SIMULATNEAOUS, SEPARATED OR TIME-SPREADED THERAPEUTIC USE | SOD CONSEILS RECH APPLIC (FR) | 2002-11-06 | — | — | EP | disclosed |
| EP-1001789-A1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-05-24 | — | — | EP | disclosed |
| EP-1001789-A1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007384-A1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-02-18 | — | — | WO | disclosed |
| WO-1999007384-A1 | PRODUCT COMPRISING AT LEAST A DOUBLE STRANDED RNA COMBINED WITH AT LEAST A 6-BENZYLURACIL DERIVATIVE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | DGKZ, DGKA, DGKG | SMN1; SMN2 4536/4885YTHDC1 3374/4885GPR84 938/4885 |
| US-20040171652-A1 | Antiviral and spermicidal contraceptives; 2-thiourea pyridinyl derivative containing compositions | ZP1, NASP, SAMHD1 | SMN1; SMN2 2941/4885YTHDC1 518/4885GPR84 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.