Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394441 | 0.89 | PKM (0.55) | PKMLCKFYNKDM4EPOLB | |
| SCHEMBL16181544 | 0.87 | KDM4E (0.63) | PKMLCKFYNKDM4EPOLB | |
| SCHEMBL7828552 | 0.87 | TSHR (0.47) | PKMLCKFYNKDM4ETPMT | |
| SCHEMBL16168327 | 0.84 | HMGCR (0.54) | PKMLCKFYNKDM4EPOLB | |
| SCHEMBL1438926 | 0.84 | PKM (0.62) | PKMLCKFYNKDM4EPOLB | |
| SCHEMBL4359214 | 0.84 | HSD17B10 (0.50) | PKMLCKFYNKDM4EPOLB | |
| SCHEMBL4299733 | 0.82 | PKM (0.60) | PKMLCKFYNKDM4EPOLB | |
| SCHEMBL9208560 | 0.82 | PKM (0.49) | PKMLCKFYNKDM4EPOLB | |
| SCHEMBL9202476 | 0.82 | PKM (0.46) | PKMLCKFYNKDM4EPOLB | |
| SCHEMBL4809375 | 0.81 | PKM (0.48) | PKMLCKFYNKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873661-B2 | Small molecule malarial Aldolase-TRAP enhancers and glideosome inhibitors | NEW YORK UNIVERSITY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9873661-B2 | Small molecule malarial Aldolase-TRAP enhancers and glideosome inhibitors | NEW YORK UNIVERSITY (US) | 2018-01-23 | — | — | US | disclosed |
| US-20140275088-A1 | SMALL MOLECULE MALARIAL ALDOLASE-TRAP ENHANCERS AND GLIDEOSOME INHIBITORS | THE JOHNS HOPKINS UNIVERSITY | 2014-09-18 | — | — | US | disclosed |
| US-20140275088-A1 | SMALL MOLECULE MALARIAL ALDOLASE-TRAP ENHANCERS AND GLIDEOSOME INHIBITORS | THE JOHNS HOPKINS UNIVERSITY | 2014-09-18 | — | — | US | disclosed |
| WO-2013063243-A1 | SMALL MOLECULE MALARIAL ALDOLASE-TRAP ENHANCERS AND GLIDEOSOME INHIBITORS | NEW YORK UNIVERSITY (US) | 2013-05-02 | — | — | WO | disclosed |
| US-5686633-A | PHOTOSTABILIZERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| CN-1098428-A | The China ink that is used for ink-jet printing | CIBA GEIGY AG (CH) | 1995-02-08 | — | — | CN | disclosed |
| CN-1026592-C | Ink for ink jet printing | CIBA GEIGY AG (CH) | 1994-11-16 | — | — | CN | disclosed |
| EP-0373574-B1 | Inks, especially for ink jet printing | CIBA GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |
| EP-0373573-B1 | Recording material for ink jet printing | CIBA GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| US-5098477-A | Aromatic ether derivatives as light stabilizers for organic materials | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| US-5073448-A | Containing light stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-12-17 | — | — | US | disclosed |
| CN-1043517-A | Ink for ink jet printing | CIBA GEIGY AG (CH) | 1990-07-04 | — | — | CN | disclosed |
| EP-0373574-A1 | Inks, especially for ink jet printing | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275088-A1 | SMALL MOLECULE MALARIAL ALDOLASE-TRAP ENHANCERS AND GLIDEOSOME INHIBITORS | ALDOA, DERA, TALDO1 | PKM 1603/4885LCK 4311/4885FYN 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.