SCHEMBL206019

SCHEMBL206019

C=Cc1ccc(CNc2ccc(Nc3ccccc3)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.46
▸ KMT2A Q03164 5/20 0.46
▸ RAB9A P51151 4/20 0.46
▸ MAPT P10636 4/20 0.46
▸ NPC1 O15118 3/20 0.46
▸ LMNA P02545 3/20 0.46
▸ NPSR1 Q6W5P4 3/20 0.46
▸ L3MBTL1 Q9Y468 3/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ MTOR P42345 1/20 0.42
▸ SIRT2 Q8IXJ6 1/20 0.42
▸ BLM P54132 3/20 0.42
▸ NSD2 O96028 2/20 0.42
▸ POLB P06746 2/20 0.42
▸ RXFP1 Q9HBX9 1/20 0.42
▸ P2RY4 P51582 6/20 0.41
▸ PKLR P30613 1/20 0.41
▸ P2RY12 Q9H244 5/20 0.39
▸ P2RY2 P41231 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6137222 0.91 RAB9A (0.49) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL6137263 0.85 RAB9A (0.60) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL1800594 0.84 LMNA (0.50) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL27562977 0.82 MAPT (0.57) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL21939350 0.80 MAPT (0.53) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL11334587 0.78 MEN1 (0.58) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL1803680 0.78 P2RY2 (0.51) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL1801932 0.77 MEN1 (0.63) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL595104 0.77 P2RY12 (0.56) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL1804471 0.75 MAPT (0.51) MEN1KMT2ARAB9AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1854490-B1 INTRAOCULAR LENS AND METHOD OF PRODUCING THE SAME HOYA CORP (JP) 2015-04-01 — — EP disclosed
EP-1810700-B1 METHOD OF PRODUCING SURFACE-TREATED INTRAOCULAR LENS AND INTRAOCULAR LENS FOR INHIBITING SECONDARY CATARACT HOYA CORP (JP) 2015-04-01 — — EP disclosed
EP-1932874-B1 METHOD FOR PRODUCING CONTACT LENS MATERIAL AND METHOD FOR PRODUCING SOFT CONTACT LENS HOYA CORP (JP) 2013-02-27 — — EP disclosed
US-8088314-B2 Process for producing surface-treated intraocular lens and intraocular lens capable of inhibiting secondary cataract HOYA CORPORATION (JP) 2012-01-03 — — US disclosed
US-7892284-B2 Intraocular lens and process for producing the same HOYA CORPORATION (JP) 2011-02-22 — — US disclosed
US-20090212450-A1 Method of manufacturing contact lens material and method of manufacturing soft contact lens HOYA CORPORATION (JP) 2009-08-27 — — US disclosed
US-20090024115-A1 Process for producing surface-treated intraocular lens and intraocular lens capable of inhibiting secondary cataract HOYA Medical Singapore Pte. Ltd. (SG) 2009-01-22 — — US disclosed
US-20080177384-A1 Intraocular Lens and Process for Producing the Same HOYA Medical Singapore Pte. Ltd. (SG) 2008-07-24 — — US disclosed
EP-1932874-A1 METHOD FOR PRODUCING CONTACT LENS MATERIAL AND METHOD FOR PRODUCING SOFT CONTACT LENS HOYA HEALTHCARE CORPORATION (JP) 2008-06-18 — — EP disclosed
EP-1854490-A1 INTRAOCULAR LENS AND METHOD OF PRODUCING THE SAME Hoya Corporation (JP) 2007-11-14 — — EP disclosed
EP-1810700-A1 METHOD OF PRODUCING SURFACE-TREATED INTRAOCULAR LENS AND INTRAOCULAR LENS FOR INHIBITING SECONDARY CATARACT Hoya Corporation (JP) 2007-07-25 — — EP disclosed
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