Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15557738 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL23609495 | 0.81 | CYP1A2 (0.48) | ALDH1A1KMT2ALMNAL3MBTL1CYP1A2 | |
| SCHEMBL29884265 | 0.81 | CYP1A2 (0.48) | ALDH1A1KMT2ALMNAL3MBTL1CYP1A2 | |
| SCHEMBL5814576 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL11465072 | 0.80 | KDM4E (0.50) | ALDH1A1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL8381483 | 0.80 | TOP1 (0.51) | ALDH1A1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL3222264 | 0.77 | CD274 (0.55) | ALDH1A1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL16583870 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2ALMNAGAAMAPT | |
| SCHEMBL2942637 | 0.76 | AAK1 (0.48) | KMT2ALMNASMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL8652704 | 0.76 | HDAC3 (0.51) | KMT2ALMNASMN1; SMN2HTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875001-B1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-01-09 | — | — | EP | disclosed |