Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | MELK | Q14680 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29884265 | 1.00 | CYP1A2 (0.48) | CYP1A2CYP2D6ALOX15ALDH1A1ABL1 | |
| SCHEMBL23609455 | 0.93 | RAB9A (0.55) | CYP1A2CYP2D6ALOX15ALDH1A1ABL1 | |
| SCHEMBL30406559 | 0.93 | RAB9A (0.55) | CYP1A2CYP2D6ALOX15ALDH1A1ABL1 | |
| SCHEMBL2964824 | 0.83 | LMNA (0.62) | ALOX15LMNAHSD17B10CNR1TSHR | |
| SCHEMBL15557738 | 0.83 | ALDH1A1 (0.49) | ALOX15ALDH1A1RAB9ALMNAHSD17B10 | |
| SCHEMBL20607642 | 0.81 | ALDH1A1 (0.56) | CYP1A2ALOX15ALDH1A1CYP2C19LMNA | |
| SCHEMBL23609322 | 0.80 | NR1H2 (0.37) | CYP1A2CYP2D6ALOX15ALDH1A1ABL1 | |
| SCHEMBL30405851 | 0.80 | NR1H2 (0.37) | CYP1A2CYP2D6ALOX15ALDH1A1ABL1 | |
| SCHEMBL23609753 | 0.80 | MAPT (0.62) | ALDH1A1RAB9ALMNAMEN1POLB | |
| SCHEMBL29975374 | 0.80 | MAPT (0.62) | ALDH1A1RAB9ALMNAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |