Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538163 | 0.80 | CA1 (0.47) | ALDH1A1CA1CA2ERN1L3MBTL1 | |
| SCHEMBL16669880 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CA1CA2ERN1L3MBTL1 | |
| SCHEMBL25368149 | 0.78 | ALDH1A1 (0.35) | ALDH1A1ERN1L3MBTL1PIM1PIM2 | |
| SCHEMBL23748164 | 0.77 | HTR2C (0.39) | ALDH1A1CA1CA2ERN1CTSL | |
| SCHEMBL20607906 | 0.76 | ERN1 (0.47) | ERN1L3MBTL1SMN1; SMN2MAPTTUBB1 | |
| SCHEMBL11926109 | 0.76 | CA1 (0.36) | ALDH1A1CA1CA2ERN1L3MBTL1 | |
| SCHEMBL6753702 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CA1CA2ERN1L3MBTL1 | |
| SCHEMBL21647646 | 0.74 | KDM1A (0.43) | ERN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL22230878 | 0.73 | CA1 (0.41) | ALDH1A1CA1CA2ERN1L3MBTL1 | |
| SCHEMBL9327164 | 0.73 | ERN1 (0.44) | ALDH1A1CA1CA2ERN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971191-A1 | BORON-CONTAINING SMALL MOLECULES | Bill And Melinda Gates Foundation (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-113563368-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-10-29 | — | — | CN | disclosed |
| CN-113321672-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-08-31 | — | — | CN | disclosed |
| EP-3423065-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2021-07-21 | — | — | EP | disclosed |
| CN-109195608-B | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-05-11 | — | — | CN | disclosed |
| US-10919916-B2 | Boron-containing small molecules | BILL & MELINDA GATES FOUNDATION (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200247827-A1 | BORON-CONTAINING SMALL MOLECULES | BILL & MELINDA GATES FOUNDATION (US) | 2020-08-06 | — | — | US | disclosed |
| US-10611780-B2 | Boron-containing small molecules | BILL AND MELINDA GATES FOUNDATION (US) | 2020-04-07 | — | — | US | disclosed |
| US-20190077814-A1 | BORON-CONTAINING SMALL MOLECULES | GATES FOUNDATION | 2019-03-14 | — | — | US | disclosed |
| EP-3423065-A1 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077814-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BTD | ALDH1A1 4559/4885CA1 3591/4885CA2 743/4885 |
| US-10919916-B2 | Boron-containing small molecules | BCL6B, BLVRB, BTD | ALDH1A1 4559/4885CA1 3591/4885CA2 743/4885 |
| US-10611780-B2 | Boron-containing small molecules | BCL6B, BLVRB, BTD | ALDH1A1 4559/4885CA1 3591/4885CA2 743/4885 |
| US-20200247827-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BTD | ALDH1A1 4559/4885CA1 3591/4885CA2 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.