Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899226 | 0.86 | SIGMAR1 (0.65) | SIGMAR1KCNH2 | |
| SCHEMBL466872 | 0.83 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| Ammonia Solution, Strong SCHEMBL20608292 | 0.82 | SIGMAR1 (0.98) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL1899223 | 0.79 | SIGMAR1 (0.91) | SIGMAR1KCNH2 | |
| SCHEMBL1896896 | 0.74 | SIGMAR1 (0.65) | SIGMAR1KCNH2 | |
| SCHEMBL1896482 | 0.72 | SIGMAR1 (0.62) | SIGMAR1KCNH2 | |
| SCHEMBL466979 | 0.72 | SIGMAR1 (0.88) | SIGMAR1KCNH2 | |
| SCHEMBL467023 | 0.71 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL731151 | 0.71 | SIGMAR1 (0.67) | SIGMAR1KCNH2 | |
| SCHEMBL467442 | 0.71 | SIGMAR1 (1.00) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190010128-A1 | 1-ARYL-3-AMINOALKOXY PYRAZOLES AS SIGMA LIGANDS ENHANCING ANALGESIC EFFECT OF OPIOIDS AND ATTENUATING THE DEPENDENCY THEREOF | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2019-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190010128-A1 | 1-ARYL-3-AMINOALKOXY PYRAZOLES AS SIGMA LIGANDS ENHANCING ANALGESIC EFFECT OF OPIOIDS AND ATTENUATING THE DEPENDENCY THEREOF | OPRK1, OPRD1, SIGMAR1 | SIGMAR1 3/4885KCNH2 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.