⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387222 | 0.80 | — | — | |
| SCHEMBL18420363 | 0.78 | KIF11 (0.31) | — | |
| SCHEMBL21309259 | 0.73 | — | — | |
| SCHEMBL10924271 | 0.72 | CYP2D6 (0.30) | — | |
| SCHEMBL8783136 | 0.71 | — | — | |
| SCHEMBL456975 | 0.71 | — | — | |
| SCHEMBL17361362 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL9763813 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL9312314 | 0.69 | KIF11 (0.33) | — | |
| SCHEMBL4445064 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820776-B2 | Process for the preparation of Remimazolam and solid state forms of Remimazolam salts | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2023-11-21 | — | — | US | claimed |
| US-20210277013-A1 | PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SOLID STATE FORMS OF REMIMAZOLAM SALTS | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2021-09-09 | — | — | US | claimed |
| US-20200239477-A1 | METHOD FOR PREPARING 3-[(4S)-8-BROMO-1-METHYL-6-(PYRIDIN-2-YL)-4H-IMIDAZO[1,2-A][1,4]BENZODIAZEPIN-4-YL]-PROPIONIC ACID METHYL ESTER, AND COMPOUNDS USEFUL IN SAID METHOD | MOEHS IBERICA, S.L. (ES) | 2020-07-30 | — | — | US | claimed |
| WO-2018148361-A1 | PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SOLID STATE FORMS OF REMIMAZOLAM SALTS | WATSON LABORATORIES INC. (US) | 2018-08-16 | — | — | WO | claimed |
| US-12540140-B2 | Process for the preparation of remimazolam | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2026-02-03 | — | — | US | disclosed |
| US-20250263414-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF REMIMAZOLAM | FRESENIUS KABI ONCOLOGY LIMITED (IN) | 2025-08-21 | — | — | US | disclosed |
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |
| EP-4504731-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF REMIMAZOLAM | Fresenius Kabi Oncology Ltd (IN) | 2025-02-12 | — | — | EP | disclosed |
| CN-112789276-B | Analgesic compounds, process for their preparation and their use in medicine | 上海海雁医药科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-112592306-B | Pyrrolinones and synthesis method thereof | 百顺药业有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-11820776-B2 | Process for the preparation of Remimazolam and solid state forms of Remimazolam salts | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2023-11-21 | — | — | US | disclosed |
| EP-4269387-A1 | PYRROLINONE COMPOUND AND SYNTHESIS METHOD THEREFOR | Poseidon Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-20120165519-A1 | Fused Bicyclic Derivatives of 2,4-Diaminopyrimidine as ALK and c-MET Inhibitors | CEPHALON, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| WO-2012085261-A1 | METHOD AND KIT FOR PROCESSING WAX-EMBEDDED BIOLOGICAL SAMPLES | QIAGEN GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
| US-8148391-B2 | Fused bicyclic derivatives of 2,4-diaminopyrimidine as ALK and c-Met inhibitors | CEPHALON, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| WO-2011104027-A1 | PROCESS FOR PARALLEL ISOLATION AND/OR PURIFICATION OF RNA AND DNA | QIAGEN GMBH (DE) | 2011-09-01 | — | — | WO | disclosed |
| EP-2222647-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | Cephalon, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| CN-101535276-A | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC (US) | 2009-09-16 | — | — | CN | disclosed |
| US-20090221555-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND c-MET INHIBITORS | CEPHALON, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| WO-2008051547-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |