SCHEMBL8783136

SCHEMBL8783136

COC(C)(CN)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2221213 0.84
SCHEMBL24773312 0.82
SCHEMBL14762326 0.78 KIF11 (0.32)
SCHEMBL27835 0.78
SCHEMBL5885257 0.76 FDPS (0.35)
SCHEMBL12254230 0.74 KDM4E (0.52)
SCHEMBL456975 0.71
SCHEMBL2060930 0.71
SCHEMBL4445064 0.69
Hydrochloric Acid SCHEMBL3175565 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5616613-A ANTITUMOR AGENTS; ISOMERS; STABLE IN WATER, SOLUBLE FOR INTRAVENOUS INJECTION TORAY INDUSTRIES, INC. (JP) 1997-04-01 US disclosed
EP-0518645-B1 Platinum (II) complex and antitumor agent TORAY INDUSTRIES (JP) 1997-01-15 EP disclosed
EP-0704453-A1 NOVEL PLATINUM (II) COMPLEX AND REMEDY FOR MALIGNANT TUMOR TORAY INDUSTRIES, INC. (JP) 1996-04-03 EP disclosed
US-5348950-A Side effect reduction TORAY INDUSTRIES, INC. (JP) 1994-09-20 US disclosed
EP-0518645-A1 Platinum (II) complex and antitumor agent TORAY INDUSTRIES, INC. (JP) 1992-12-16 EP disclosed