Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27829596 | 0.95 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HSD17B10MAPTGAA | |
| SCHEMBL27765963 | 0.86 | KDM4E (0.44) | ALDH1A1MAPTL3MBTL1KDM4EDRD2 | |
| SCHEMBL2951395 | 0.74 | ALOX5 (0.43) | ALDH1A1SMN1; SMN2HSD17B10MAPTGAA | |
| SCHEMBL18670789 | 0.73 | STAT3 (0.32) | — | |
| SCHEMBL27809098 | 0.72 | GABRA1 (0.33) | — | |
| SCHEMBL9404986 | 0.70 | STAT3 (0.45) | — | |
| SCHEMBL2950385 | 0.68 | BRD4 (0.40) | ALDH1A1SMN1; SMN2MAPTGAALMNA | |
| SCHEMBL3237435 | 0.68 | MGAM (0.36) | MAPTGAARXFP1 | |
| SCHEMBL31471705 | 0.67 | CDC25A (0.37) | HSD17B10GAAL3MBTL1KDM4E | |
| SCHEMBL8003382 | 0.66 | NPC1 (0.40) | ALDH1A1SMN1; SMN2HSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200282076-A1 | AMPHIPHILIC DYE-COATED INORGANIC NANOPARTICLE CLUSTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-09-10 | — | — | US | claimed |
| WO-2019010329-A1 | AMPHIPHILIC DYE-COATED INORGANIC NANOPARTICLE CLUSTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-01-10 | — | — | WO | claimed |
| US-20200282076-A1 | AMPHIPHILIC DYE-COATED INORGANIC NANOPARTICLE CLUSTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-09-10 | — | — | US | disclosed |
| WO-2019010329-A1 | AMPHIPHILIC DYE-COATED INORGANIC NANOPARTICLE CLUSTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-01-10 | — | — | WO | disclosed |