Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | SELP | P16109 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20613738 | 1.00 | FAAH (0.56) | FAAHNAAADNM1CASP2SELP | |
| SCHEMBL20613633 | 1.00 | FAAH (0.56) | FAAHNAAADNM1CASP2SELP | |
| SCHEMBL20613639 | 0.93 | NAAA (0.47) | FAAHNAAADNM1CASP2SELP | |
| SCHEMBL20613667 | 0.86 | CASP2 (0.48) | FAAHNAAACASP2ALDH1A1HPGD | |
| SCHEMBL31235537 | 0.84 | FAAH (0.58) | FAAHNAAADNM1CASP2SELP | |
| SCHEMBL25008200 | 0.82 | FAAH (0.77) | FAAHNAAADNM1CASP2SELP | |
| SCHEMBL135555 | 0.82 | FAAH (0.77) | FAAHNAAADNM1CASP2SELP | |
| SCHEMBL846255 | 0.82 | FAAH (0.77) | FAAHNAAADNM1CASP2SELP | |
| SCHEMBL25350370 | 0.82 | FAAH (0.77) | FAAHNAAADNM1CASP2SELP | |
| SCHEMBL14576744 | 0.82 | FAAH (0.77) | FAAHNAAADNM1CASP2SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215496-B1 | PANTOTHENAMIDE ANALOGUES | RADBOUD UNIV MEDISCH CENTRUM (NL) | 2019-01-02 | — | — | EP | disclosed |