Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097866 | 0.85 | BCL2L1 (0.59) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL15697571 | 0.79 | GPR35 (0.61) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL8250577 | 0.79 | BCL2L1 (0.61) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL5600103 | 0.78 | BCL2L1 (0.59) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL156320 | 0.78 | BCL2L1 (0.59) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL31435451 | 0.78 | BCL2L1 (0.59) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL1090344 | 0.78 | BCL2L1 (0.59) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL20614582 | 0.78 | BCL2L1 (0.59) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL498133 | 0.78 | BCL2L1 (0.59) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL121300 | 0.78 | HDAC1 (0.70) | BCL2L1GPR35TBXAS1HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421464-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AS WELL AS PREPARATION METHOD AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2019-01-02 | — | — | EP | disclosed |