Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408830 | 1.00 | MEN1 (0.50) | MEN1KMT2ANOTUMTNKSPARP1 | |
| SCHEMBL69754 | 0.89 | NOTUM (0.46) | MEN1KMT2ANOTUMTNKSPARP1 | |
| SCHEMBL12945193 | 0.78 | KMT2A (0.50) | MEN1KMT2ANOTUMCYP2A6MAOA | |
| SCHEMBL20622381 | 0.78 | KMT2A (0.50) | MEN1KMT2ANOTUMCYP2A6MAOA | |
| SCHEMBL28292050 | 0.78 | MEN1 (0.50) | MEN1KMT2ANOTUMCYP2A6MAOA | |
| SCHEMBL642025 | 0.77 | NOTUM (0.70) | MEN1KMT2ANOTUMALDH1A1LMNA | |
| SCHEMBL30776885 | 0.76 | NOTUM (0.58) | MEN1KMT2ANOTUMALDH1A1LMNA | |
| SCHEMBL6366299 | 0.76 | NOTUM (0.58) | MEN1KMT2ANOTUMALDH1A1LMNA | |
| SCHEMBL20614744 | 0.76 | PLK1 (0.39) | MEN1KMT2ATNKSPARP1TNKS2 | |
| SCHEMBL22578173 | 0.76 | MAOA (0.51) | MEN1KMT2ATNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |