Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 3/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20614680 | 0.91 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL11910402 | 0.85 | KDM4E (0.70) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| Bromide SCHEMBL19689589 | 0.84 | KDM4E (0.69) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL19689605 | 0.84 | KDM4E (0.69) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL12797278 | 0.83 | KDM4E (0.63) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL20619601 | 0.80 | KDM4E (0.57) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL20599149 | 0.80 | KDM4E (0.57) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL20614931 | 0.79 | KDM4E (0.55) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL19454421 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL20614760 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851115-B2 | Heterocyclic compounds as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-12-01 | — | — | US | disclosed |
| WO-2019006291-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |
| US-20190002478-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002478-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | SIRT1, FURIN, SIRT5 | ALDH1A1 721/4885KDM4E 1342/4885HPGD 157/4885 |
| US-10851115-B2 | Heterocyclic compounds as RSV inhibitors | SIRT1, FURIN, SIRT5 | ALDH1A1 721/4885KDM4E 1342/4885HPGD 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.