Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20614943 | 0.91 | CYP11B2 (0.39) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20614703 | 0.84 | CYP11B2 (0.39) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL20614949 | 0.83 | KDM4E (0.43) | ALDH1A1KDM4EL3MBTL1HPGDRAB9A | |
| SCHEMBL20618170 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EL3MBTL1HPGDMEN1 | |
| SCHEMBL20618257 | 0.78 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1HPGDRAB9A | |
| SCHEMBL20614758 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EL3MBTL1HPGDMEN1 | |
| SCHEMBL20614957 | 0.75 | CYP11B2 (0.41) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL20619531 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EL3MBTL1HPGDMEN1 | |
| SCHEMBL20598711 | 0.74 | MAPT (0.44) | KDM4EL3MBTL1RAB9AMAPTTP53 | |
| SCHEMBL20614721 | 0.73 | LMNA (0.42) | ALDH1A1HPGDKMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006291-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |