Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28791205 | 1.00 | KDM4E (0.69) | KDM4EMAPTEGFRALDH1A1CISD1 | |
| SCHEMBL28791206 | 0.86 | MAPT (0.63) | KDM4EMAPTEGFRALDH1A1HPGD | |
| SCHEMBL28820743 | 0.86 | MCL1 (0.66) | KDM4EMAPTEGFRALDH1A1HPGD | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL29881895 | 0.82 | KDM4E (1.00) | KDM4EMAPTEGFRALDH1A1CISD1 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL1285555 | 0.82 | KDM4E (1.00) | KDM4EMAPTEGFRALDH1A1CISD1 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL2057244 | 0.82 | KDM4E (1.00) | KDM4EMAPTEGFRALDH1A1CISD1 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL1285559 | 0.82 | KDM4E (1.00) | KDM4EMAPTEGFRALDH1A1CISD1 | |
| SCHEMBL21457438 | 0.82 | MAPT (0.74) | KDM4EMAPTALDH1A1HPGDPOLB | |
| SCHEMBL21457441 | 0.82 | MAPT (0.74) | KDM4EMAPTALDH1A1HPGDPOLB | |
| SCHEMBL26081115 | 0.81 | EGFR (0.59) | KDM4EEGFRALDH1A1CISD1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-01-25 | — | — | US | disclosed |
| US-11787804-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230114220-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-13 | — | — | US | disclosed |
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-06 | — | — | US | disclosed |
| US-20220153738-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-05-19 | — | — | US | disclosed |
| US-11312714-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-26 | — | — | US | disclosed |
| WO-2021127482-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENT OF THE UNIVERSITY OFCALIFORNIA (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2020142413-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-09 | — | — | WO | disclosed |
| US-20200157093-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-05-21 | — | — | US | disclosed |
| WO-2019006359-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230114220-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | KDM4E 1615/4885MAPT 2371/4885EGFR 2010/4885 |
| US-20200157093-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | KDM4E 1615/4885MAPT 2371/4885EGFR 2010/4885 |
| US-11312714-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | KDM4E 1615/4885MAPT 2371/4885EGFR 2010/4885 |
| US-11787804-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | KDM4E 1615/4885MAPT 2371/4885EGFR 2010/4885 |
| US-20220153738-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | KDM4E 1615/4885MAPT 2371/4885EGFR 2010/4885 |
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | KDM4E 1615/4885MAPT 2371/4885EGFR 2010/4885 |
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | MKI67, CYP17A1, CYP21A2 | KDM4E 973/4885MAPT 4518/4885EGFR 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.