Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486263 | 0.85 | GAA (0.54) | GAAKDM4ELMNAPOLBCYP1A2 | |
| SCHEMBL17723954 | 0.77 | ACHE (0.59) | FDPSTUBB1KDM4ELMNAPOLB | |
| SCHEMBL10134070 | 0.77 | ALDH1A1 (0.44) | GAALMNAMAPTALDH1A1TSHR | |
| SCHEMBL17941258 | 0.76 | FDPS (0.75) | FDPSKDM4ELMNAPOLBCYP1A2 | |
| SCHEMBL21305440 | 0.74 | TTR (0.61) | GAAKDM4ELMNAPOLBRAB9A | |
| SCHEMBL5002325 | 0.74 | ALDH1A1 (0.71) | GAAKDM4ELMNAPOLBMAPT | |
| SCHEMBL4466531 | 0.73 | SMN1; SMN2 (0.55) | GAALMNAPOLBMAPTNPC1 | |
| SCHEMBL5638416 | 0.73 | TUBB1 (0.46) | TUBB1GAAKDM4ELMNAPOLB | |
| SCHEMBL12555538 | 0.73 | GRM4 (0.47) | GAAKDM4ELMNAPOLBMAPT | |
| SCHEMBL8022330 | 0.73 | ALDH1A1 (0.50) | GAAKDM4ELMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3612188-B1 | HETEROBIVALENT LIGANDS SUITABLE FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | T C ISTANBUL MEDIPOL UNIV (TR) | 2023-12-13 | — | — | EP | disclosed |
| WO-2019004970-A2 | HETEROBIVALENT LIGANDS SUITABLE FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | T.C. İSTANBUL MEDİPOL ÜNİVERSİTESİ (TR) | 2019-01-03 | — | — | WO | disclosed |